CACNA1A Products

Antibodies
CACNA1A Antibody
CACNA1A Antibody
NBP2-38049
Species: Hu, Mouse
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Proteins
CACNA1A Recombinant Protein A ...
CACNA1A Recombinant Protein Antigen
NBP2-38049PEP
Species: Hu
Applications: AC
RNAi
CACNA1A RNAi
CACNA1A RNAi
H00000773-R01
Species: Hu
CACNA1A RNAi
CACNA1A RNAi
H00000773-R02
Species: Hu

Description

FUNCTION: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q-type calcium currents. P/Q-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by the funnel toxin (Ftx) and by the omega-agatoxin-IVA (omega-Aga-IVA). They are however insensitive to dihydropyridines (DHP), and omega-conotoxin-GVIA (omega-CTx-GVIA).; SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.; Tissue specificity: Brain specific; mainly found in cerebellum, cerebral cortex, thalamus and hypothalamus. No expression in heart, kidney, liver or muscle. Purkinje cells contain predominantly P-type VSCC, the Q-type being a prominent calcium current in cerebellar granule cells.

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 773
Alternate Names
  • Calcium channel, L type, alpha-1 polypeptide isoform 4
  • SCA6
  • CACN3
  • BI
  • CACH4
  • Voltage-gated calcium channel subunit alpha Cav2.1
  • voltage-dependent P/Q-type calcium channel subunit alpha-1A
  • Brain calcium channel I
  • calcium channel, L type, alpha-1 polypeptide
  • HPCA
  • brain calcium channel 1
  • FHM
  • MHP1
  • EA2
  • MHP
  • APCA
  • CACNL1A4CAV2.1
  • Cav2.1
  • calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

PTMs for CACNA1A

Learn more about PTMs related to CACNA1A.

Phosphorylation
Methylation
Dephosphorylation

Bioinformatics Tool for CACNA1A

Discover related pathways, diseases and genes to CACNA1A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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