c-Abl Products

Antibodies
c-Abl [p Tyr412] Antibody
c-Abl [p Tyr412] Antibody
NSB252
Species: Hu, Rt, Mouse
Applications: WB
Host: Rabbit Polyclonal
c-Abl Antibody [Unconjugated] ...
c-Abl Antibody [Unconjugated]
AF5414
Species: Hu
Applications: WB, Simple Western
Host: Goat Polyclonal
c-Abl Antibody
c-Abl Antibody
NBP2-15631
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
c-Abl Overexpression Lysate ( ...
c-Abl Overexpression Lysate (Native)
NBL1-07208
Applications: WB
c-Abl Overexpression Lysate ( ...
c-Abl Overexpression Lysate (Native)
NBL1-07209
Applications: WB
Proteins
c-Abl Recombinant Protein Ant ...
c-Abl Recombinant Protein Antigen
NBP1-90289PEP
Species: Hu
Applications: AC
c-Abl Recombinant Protein Ant ...
c-Abl Recombinant Protein Antigen
NBP1-90287PEP
Species: Hu
Applications: AC
c-Abl Recombinant Protein Ant ...
c-Abl Recombinant Protein Antigen
NBP1-90288PEP
Species: Hu
Applications: AC
RNAi
c-Abl RNAi
c-Abl RNAi
H00000025-R05
Species: Hu
c-Abl RNAi
c-Abl RNAi
H00000025-R06
Species: Hu

Description

c-Abl is the human cellular homolog of a the v-Abl viral oncogene. v-Abl was originally discovered as a mouse cell-derived sequence in the genome of the Abelson murine leukemia virus (A-MuLV), a transforming retrovirus isolated by the laboratory of Dr. H.T. Abelson. c-Abl is a tyrosine kinase from the Src-family of tyrosine kinases that localizes to both the cytoplasm and nucleus. It bears an SH2 (src-homology 2) and SH3 (src-homology 3) domain responsible for mediating c-Abl protein-protein interactions. c-Abl is implicated to play a role in multiple cellular processes such as cell cycle checkpoint signaling, apoptosis, cell differentiation, cell adhesion, and transcriptional regulation. Chromosomal translocations involving the c-Abl gene are associated with human leukemias.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 25
Alternate Names
  • EC 2.7.10
  • ABL
  • Abelson murine leukemia viral oncogene homolog 1
  • Proto-oncogene c-Abl
  • v-abl
  • v-abl Abelson murine leukemia viral oncogene homolog 1
  • tyrosine-protein kinase ABL1
  • c-abl oncogene 1, receptor tyrosine kinase
  • proto-oncogene tyrosine-protein kinase ABL1
  • c-ABL
  • p150bcr/c-abl oncogene protein
  • JTK7bcr/abl
  • EC 2.7.10.2
  • c-abl oncogene 1, non-receptor tyrosine kinase

Research Areas for c-Abl

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Cycle and Replication
Cytoskeleton Markers
DNA Repair
Phospho-Specific
Signal Transduction
Tumor Suppressors

PTMs for c-Abl

Learn more about PTMs related to c-Abl.

Phosphorylation
Methylation
Demethylation
Cleavage
Myristoylation

Bioinformatics Tool for c-Abl

Discover related pathways, diseases and genes to c-Abl. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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