BNP Products

Description

Brain natriuretic peptide (BNP) circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. BNP is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. BNP belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic peptides (eleven of the 17 amino acid residues are homologous in the ring of each of the natriuretic peptides, see fig. 18). BNP is a 32 amino acid peptide with disulfide bond between the cystein residues Cys10 and Cys26. In earlier studies it has been demonstrated that BNP concentration in blood increases with the severity of congestive heart failure. Quantitative measurement of BNP in blood provides an objective indicator of congestive heart failure severity

Bioinformatics

Entrez	4879 Human
Uniprot	AAH25785 Human NP_002512.1 Human P16860 Human
Product By Gene ID	4879
Alternate Names	BNP brain type natriuretic peptide Gamma-brain natriuretic peptide natriuretic peptide B natriuretic peptide precursor B natriuretic peptides B natriuretic protein

Research Areas for BNP

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research
Immunology
Neuroscience
Neurotransmission