Species: Hu
Applications: WB, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Bv
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. [provided by RefSeq]
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Human
|
| Product By Gene ID |
8412 |
| Alternate Names |
- breast cancer estrogen resistance 3
- dJ1033H22.2 (breast cancer estrogen resistance 3)
- KIAA0554
- Novel SH2-containing protein 2
- NSP2SH2D3Bbreast cancer estrogen resistance protein 3
- SH2 domain-containing protein 3B
|
Research Areas for BCAR3
Find related products by research area and learn more about each of the different research areas below.
Cell Cycle and Replication
