ATP6V1E1 Products

Description

ATP6V1E1 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome. [provided by RefSeq]

Bioinformatics

Entrez	529 Human
Uniprot	AAH04443 Human NM_001696 Human NP_001687 Human NP_001687.1 Human P36543 Human
Product By Gene ID	529
Alternate Names	ATP6E2ATP6V1E ATP6E31kDa subunit ATPase, H+ transporting, lysosomal (vacuolar proton pump) 31kD ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E isoform 1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 H+-transporting ATP synthase chain E, vacuolar p31 Vacuolar proton pump subunit E 1 V-ATPase 31 kDa subunit V-ATPase subunit E 1 V-ATPase, subunit E Vma4 V-type proton ATPase subunit E 1