ATG4B Products

Antibodies
ATG4B Antibody
ATG4B Antibody
NBP2-24709
Species: Hu, Mu, Rt
Applications: WB, IHC-P
Host: Rabbit Polyclonal
ATG4B Antibody
ATG4B Antibody
NBP2-24735
Species: Hu, Mu, Bv
Applications: WB
Host: Rabbit Polyclonal
ATG4B Antibody
ATG4B Antibody
NBP2-41307
Species: Hu, Mu, Rt, Bv
Applications: WB, ELISA, IHC, IHC-P, ICC/IF
Host: Rabbit Polyclonal
Lysates
ATG4B Knockout HeLa Cell Lysa ...
ATG4B Knockout HeLa Cell Lysate
NBP2-65357
Species: Hu
Applications: WB
ATG4B Overexpression Lysate
ATG4B Overexpression Lysate
NBL1-07797
Species: Hu
Applications: WB
ATG4B Overexpression Lysate ( ...
ATG4B Overexpression Lysate (Native)
NBP2-09850
Species: Hu
Applications: WB
Proteins
Recombinant Human His6-ATG4B ...
Recombinant Human His6-ATG4B Prote...
E-400
Species: Hu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
ATG4B Recombinant Protein Ant ...
ATG4B Recombinant Protein Antigen
NBP2-57210PEP
Species: Hu
Applications: AC
Recombinant Human ATG4B Prote ...
Recombinant Human ATG4B Protein
NBP1-99088
Species: Hu
Applications: PAGE

Description

FUNCTION: Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. ENZYME REGULATION: Inhibited by N-ethylmaleimide. SUBCELLULAR LOCATION: Cytoplasm (Probable). ALTERNATIVE PRODUCTS: 5 named isoforms produced by alternative splicing.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 23192
Alternate Names
  • DKFZp586D1822
  • EC 3.4.22
  • Apg4B
  • EC 3.4.22.-
  • hAPG4B
  • Autophagin-1
  • AUT-like 1 cysteine endopeptidase
  • cysteine protease ATG4B
  • APG4B
  • autophagin-1
  • Autophagy-related protein 4 homolog B
  • APG4 autophagy 4 homolog B
  • Autophagy-related cysteine endopeptidase 1
  • KIAA0943
  • AUTL1MGC1353
  • APG4 autophagy 4 homolog B (S. cerevisiae)
  • ATG4 autophagy related 4 homolog B (S. cerevisiae)

Research Areas for ATG4B

Find related products by research area and learn more about each of the different research areas below.

Autophagy
Cancer
Phospho-Specific

PTMs for ATG4B

Learn more about PTMs related to ATG4B.

Cleavage
Phosphorylation
Reduction

Bioinformatics Tool for ATG4B

Discover related pathways, diseases and genes to ATG4B. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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Related ATG4B Blog Posts

Check out the latest blog posts on ATG4B.
Animal Models to Study Autophagy
By Christina Towers, PhD What is autophagy?Autophagy is the catabolic process that degrades cytoplasmic material via the lysosome. In the beginning... the process of macroautophagy was originally characterized in...    Read more.
Best Methods to Induce and Inhibit Autophagy Pharmacologically
By Christina Towers, PhD Autophagy facilitates the degradation and recycling of damaged cytoplasmic material. The multistep process consists of a double membrane structure called an autophagosome that engulfs proteins...    Read more.
ATG4B - a cysteine protease involved in autophagosome elongation
Autophagy can be broken down into 4 main stages: phagophore nucleation, autophagosome elongation, autophagosome docking and fusion with a lysosome, and vesicle breakdown and degradation. ATG4B is one of four ATG4 homologs (ATG4A, ATG4B, ATG4C, and...    Read more.
Read more ATG4B related blogs.