ATG4A Products

ATG4A Antibody (514914)
ATG4A Antibody (514914)
Species: Hu, Mu
Applications: WB, IP, ICC/IF
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
ATG4A Antibody [Unconjugated] ...
ATG4A Antibody [Unconjugated]
Species: Hu
Applications: WB, IP
Host: Sheep Polyclonal
Formulation Catalog # Availability Price  
ATG4A Antibody
ATG4A Antibody
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Recombinant Human ATG4A GST ( ...
Recombinant Human ATG4A GST (N-Ter...
Species: Hu
Applications: WB, ELISA, PA, AP
ATG4A Recombinant Protein Ant ...
ATG4A Recombinant Protein Antigen
Species: Hu
Applications: AC
ATG4A Recombinant Protein Ant ...
ATG4A Recombinant Protein Antigen
Species: Hu
Applications: AC


Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.; FUNCTION: Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.; ENZYME REGULATION: Inhibited by N-ethylmaleimide; SUBCELLULAR LOCATION: Cytoplasm;


Entrez Human
Uniprot Human
Product By Gene ID 115201
Alternate Names
  • EC 3.4.22
  • AUT-like 2, cysteine endopeptidase (S. cerevisiae)
  • EC 3.4.22.-
  • APG4 autophagy 4 homolog A (S. cerevisiae)
  • Autophagin-2
  • hAPG4A
  • cysteine protease ATG4A
  • AUT-like 2 cysteine endopeptidase
  • autophagin-2
  • AUTL2
  • autophagin 2
  • APG4A
  • cysteine endopeptidase
  • ATG4 autophagy related 4 homolog A (S. cerevisiae)

Research Areas for ATG4A

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PTMs for ATG4A

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Bioinformatics Tool for ATG4A

Discover related pathways, diseases and genes to ATG4A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.

Related ATG4A Blog Posts

Check out the latest blog posts on ATG4A.
ATG4A - protease that initiates ATG8 lipidation during autophagosome elongation
There are 3 major autophagy pathways- microautophagy, chaperone-mediated autophagy, and macroautophagy. Macroautophagy is the pathway herein referred to as simply autophagy. Autophagy can be broken down into 4 main stages: phagophore nucleatio...    Read more.
Read more ATG4A related blogs.