Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Pm, RM
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
Pentanucleotide repeat expansions in the ATXN10/SCA10 gene have been linked to spinocerebellar ataxia type 10, a disorder that is characterized by gait ataxia, cognitive development, and seizures. ATXN10/SCA10 is an evolutionarily conserved protein whose function has not been identified. It is proposed that the repeats in ATXN10/SCA10 may form unusual RNA hairpin structures that result in toxic RNA that may have biological effects such as sequestering of proteins, activation of enzymes, and deregulation of gene expression via the RNA interference pathway. ATXN10/SCA10 is also known as ataxin-10, spinocerebellar ataxia type 10 protein, brain protein E46 homolog, E46L, and FLJ37990.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
25814 |
| Alternate Names |
- ataxin 10
- ataxin-10
- Brain protein E46 homolog
- E46L
- FLJ37990
- HUMEEP
- SCA10spinocerebellar ataxia 10
- Spinocerebellar ataxia type 10 protein
|
