Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Mouse Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described.
Bioinformatics
| Uniprot |
Human |
| Product By Gene ID |
140460 |
| Alternate Names |
- ankyrin repeat and SOCS box containing 7
- ankyrin repeat and SOCS box protein 7
- ankyrin repeat and SOCS box-containing 7
- ASB-7
- FLJ22551
- FLJ25192
|
Research Areas for ASB7
Find related products by research area and learn more about each of the different research areas below.
Signal Transduction