APH1A Products

Antibodies
APH1A Antibody
APH1A Antibody
NB100-74360
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IP, ChIP
Host: Rabbit Polyclonal
APH1A Antibody
APH1A Antibody
NBP2-27176
Species: Hu, Mu, Rt, Bv, Ca, Eq, Ma-Op, Pm, Pm
Applications: WB
Host: Rabbit Polyclonal
APH1A Antibody (665404)
APH1A Antibody (665404)
MAB6908
Species: Hu
Applications: IHC
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
Lysates
APH1A Overexpression Lysate
APH1A Overexpression Lysate
NBP2-04350
Species: Hu
Applications: WB
APH1A Overexpression Lysate
APH1A Overexpression Lysate
NBP2-08465
Species: Hu
Applications: WB

Description

Anterior Pharynx Defective 1 (APH1a) is an integral transmembrane protein forming a component of the gamma-secretase complex, a complex composed of a presenilin homodimer (PSEN1 or PSEN2), nicastrin (NCSTN), APH1 (APH1A or APH1B) and PEN2. The gamma-secretase complex is an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein).

Bioinformatics

Entrez Mouse
Human
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 51107
Alternate Names
  • 6530402N02Rik
  • anterior pharynx defective 1 homolog A (C. elegans)
  • APH-1
  • APH-1a
  • APH-1A
  • Aph-1alpha
  • aph-1alpha
  • CGI-78
  • gamma-secretase subunit APH-1A
  • Presenilin-stabilization factor
  • PSF

Research Areas for APH1A

Find related products by research area and learn more about each of the different research areas below.

GPCR
Neuroscience
Stem Cell Markers