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APH1A Products

Antibodies
Lysates
APH1A Overexpression Lysate
APH1A Overexpression Lysate
NBP2-04350
Species: Hu
Applications: WB
APH1A Overexpression Lysate
APH1A Overexpression Lysate
NBP2-08465
Species: Hu
Applications: WB

Description

APH1 is a multipass transmembrane protein that interacts with presenilin (see PSEN1; MIM 104311) and nicastrin (APH2; MIM 605254) as a functional component of the gamma-secretase complex. The gamma-secretase complex is required for the intramembrane proteolysis of a number of membrane proteins, including the amyloid-beta precursor protein (APP; MIM 104760) and Notch (MIM 190198).[supplied by OMIM]

Bioinformatics

Uniprot Human
Product By Gene ID 51107
Alternate Names
  • 6530402N02Rik
  • anterior pharynx defective 1 homolog A (C. elegans)
  • APH-1
  • APH1A
  • APH-1A
  • aph-1alpha
  • CGI-78
  • gamma-secretase subunit APH-1A
  • Presenilin-stabilization factor
  • PSF

Research Areas for APH1A

Find related products by research area and learn more about each of the different research areas below.

Neuroscience
Stem Cell Markers