WB, ChIP, ICC/IF, IHC, IHC-Fr, IHC-P, IPHost:
Species: Hu, Mu, Rt, Bv, Ca, Eq, Ma-Op, Pm, Pm
Host: Rabbit Polyclonal
Host: Mouse Monoclonal
Anterior Pharynx Defective 1 (APH1a) is an integral transmembrane protein forming a component of the gamma-secretase complex, a complex composed of a presenilin homodimer (PSEN1 or PSEN2), nicastrin (NCSTN), APH1 (APH1A or APH1B) and PEN2. The gamma-secretase complex is an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein).
Bioinformatics Tool for APH1A
Discover related pathways, diseases and genes to APH1A. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.