Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IP, ChIP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Bv, Ca, Eq, Ma-Op, Pm, Pm
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Description
Anterior Pharynx Defective 1 (APH1a) is an integral transmembrane protein forming a component of the gamma-secretase complex, a complex composed of a presenilin homodimer (PSEN1 or PSEN2), nicastrin (NCSTN), APH1 (APH1A or APH1B) and PEN2. The gamma-secretase complex is an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein).
Bioinformatics
Entrez |
Mouse Human |
Uniprot |
Human Human Human Human Human Human Human Human Human Human Human Human |
Product By Gene ID |
51107 |
Alternate Names |
- 6530402N02Rik
- anterior pharynx defective 1 homolog A (C. elegans)
- APH-1
- APH-1a
- APH-1A
- Aph-1alpha
- aph-1alpha
- CGI-78
- gamma-secretase subunit APH-1A
- Presenilin-stabilization factor
- PSF
|