Apc2 Products

Description

Apc2 ia a large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation.

Bioinformatics

Entrez	10297 Human
Uniprot	BAA34611 Human BAA34611 Human NP_037498 Human NP_037498 Human O95996 Human O95996 Human
Product By Gene ID	10297
Alternate Names	adenomatosis polyposis coli 2 adenomatous polyposis coli like adenomatous polyposis coli protein 2 APCL

Research Areas for Apc2

Find related products by research area and learn more about each of the different research areas below.

Cell Biology
Cell Cycle and Replication
Ubiquitin Proteasome Pathway