Apc11 Products

Antibodies
Apc11 Antibody (3F5)
Apc11 Antibody (3F5)
NBP2-45493
Species: Hu, Mk
Applications: WB, IHC, IF
Host: Mouse monoclonal
Apc11 Antibody
Apc11 Antibody
NBP1-90140
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Apc11 Antibody
Apc11 Antibody
NBP1-90139
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
Apc11 Overexpression Lysate ( ...
Apc11 Overexpression Lysate (Native)
NBL1-07514
Applications: WB
Apc11 Overexpression Lysate ( ...
Apc11 Overexpression Lysate (Native)
NBP2-10734
Applications: WB
Apc11 Overexpression Lysate ( ...
Apc11 Overexpression Lysate (Native)
NBP2-10732
Applications: WB
Proteins
Apc11 Recombinant Protein
Apc11 Recombinant Protein
H00051529-P01
Species: Hu
Applications: WB, ELISA, PA
Apc11 Recombinant Protein Ant ...
Apc11 Recombinant Protein Antigen
NBP1-90139PEP
Species: Hu
Applications: AC
Apc11 Recombinant Protein Ant ...
Apc11 Recombinant Protein Antigen
NBP1-90140PEP
Species: Hu
Applications: AC
RNAi
Apc11 RNAi
Apc11 RNAi
H00051529-R03
Species: Hu
Applications: RNAi, RNAi SP
Apc11 RNAi
Apc11 RNAi
H00051529-R04
Species: Hu
Applications: RNAi, RNAi SP
Apc11 RNAi
Apc11 RNAi
H00051529-R06
Species: Hu
Applications: RNAi, RNAi SP

Description

APC11 (anaphase-promoting complex subunit 11) is a member of the E3 enzyme family. This protein contains a RING-H2 domain and has a molecular weight of approximately 9.8 kD. The APC11 protein is distributed diffusely in the cytoplasm and is located in the nucleus with discrete accumulation in granular structures. The APC11 protein is a probable catalytic unit in the APC complex. The APC11 protein functions with other members of the APC complex as a multisubunit cell cycle ubiquitin ligase, and a regulator of sister chromatid separation by degrading securins. In addition, this protein functions in ubiquitin-dependent cyclin catabolism, metaphase/anaphase transition, and spindle elongation. The APC11 protein comprises one subunit of the anaphase promoting complex including APC1-8, and other probable complex proteins APC9-11, Cdc26, Mnd2, Swm1. The APC complex is inactivated by protein kinase A and is activated by CDC20 and Cdh1. In addition to the APC complex proteins, APC11 has been shown to interact with Ubc4. The Poly6116 antibody has been shown to be useful for Western blotting of the human and mouse APC11 protein.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 51529
Alternate Names
  • APC11 anaphase promoting complex subunit 11 homolog
  • anaphase promoting complex subunit 11 (yeast APC11 homolog)
  • anaphase-promoting complex subunit 11
  • MGC882
  • HSPC214
  • Apc11p
  • APC11Hepatocellular carcinoma-associated RING finger protein
  • Cyclosome subunit 11
  • anaphase promoting complex subunit 11

Pathways for Apc11

View related products by pathway and learn more about each of the pathways below.

Cell Activation
Translation
T Cell Activation
Pathogenesis
Anaphase

Research Areas for Apc11

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication

Bioinformatics Tool for Apc11

Discover related pathways, diseases and genes to Apc11. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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