Anthrax LF Products

Antibodies
Anthrax LF Antibody
Anthrax LF Antibody
NB100-56666
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Anthrax LF Antibody
Anthrax LF Antibody
NB100-56667
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Proteins
Anthrax LF Peptide
Anthrax LF Peptide
NBP1-76437PEP
Species: Ba
Applications: AC
Anthrax LF Peptide
Anthrax LF Peptide
NBP1-76436PEP
Species: Ba
Applications: AC

Description

Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three of the proteins must be present for toxicity to occur. It begins with the binding of PA to its cell-surface receptor, ATR (Anthrax Toxin Receptor), at which point PA is cleaved and the resulting 63 kD carboxyl-terminal fragment binds to LF and EF. LF is a protease that is known to cleave members of the mitogen-activated protein kinase kinase (MAPKK) family (2).

Bioinformatics

Alternate Names
  • Anthrax lethal factor
  • LF
  • Lef
  • bacillus anthracis lethal factor
  • B.anthracis lethal factor
  • Anthrax LF
  • Anthrax lethal toxin endopeptidase component

Research Areas for Anthrax LF

Find related products by research area and learn more about each of the different research areas below.

Immunology
Virology, Bacteria and Parasites