Ankyrin 1 Products

Antibodies
Ankyrin 1 Antibody
Ankyrin 1 Antibody
NBP2-33806
Species: Hu, Mouse
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Ankyrin 1 Antibody
Ankyrin 1 Antibody
NBP1-71805
Species: Hu, Primate
Applications: WB, IP
Host: Rabbit Polyclonal
Ankyrin 1 Antibody
Ankyrin 1 Antibody
NBP1-90168
Species: Hu, Mouse
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
Ankyrin 1 Antibody Pair
Ankyrin 1 Antibody Pair
H00000286-PW1
Species: Hu
Applications: WB, IP
Lysates
Ankyrin 1 Overexpression Lysa ...
Ankyrin 1 Overexpression Lysate (N...
NBP2-06638
Applications: WB
Ankyrin 1 Overexpression Lysa ...
Ankyrin 1 Overexpression Lysate (D...
H00000286-T01
Species: Hu
Applications: WB
Proteins
Ankyrin 1 Recombinant Protein ...
Ankyrin 1 Recombinant Protein
H00000286-P01
Species: Hu
Applications: WB, ELISA, PA
Ankyrin 1 Recombinant Protein ...
Ankyrin 1 Recombinant Protein Antigen
NBP1-90168PEP
Species: Hu
Applications: AC
Ankyrin 1 Recombinant Protein ...
Ankyrin 1 Recombinant Protein Antigen
NBP2-33806PEP
Species: Hu
Applications: AC
RNAi
Ankyrin 1 RNAi
Ankyrin 1 RNAi
H00000286-R03
Species: Hu
Applications: RNAi, RNAi SP
Ankyrin 1 RNAi
Ankyrin 1 RNAi
H00000286-R05
Species: Hu
Applications: RNAi, RNAi SP
Ankyrin 1 RNAi
Ankyrin 1 RNAi
H00000286-R06
Species: Hu
Applications: RNAi, RNAi SP

Description

Ankyrins are a family of proteins that link the integral membrane proteins to the underlying spectrin-actincytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact and themaintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various targetproteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed ofthree structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highlyconserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subjectto variation. Ankyrin 1, the prototype of this family, was first discovered in the erythrocytes, but since has alsobeen found in brain and muscles. Mutations in erythrocytic ankyrin 1 have been associated in approximately half of allpatients with hereditary spherocytosis. Complex patterns of alternative splicing in the regulatory domain, giving riseto different isoforms of ankyrin 1 have been described. Truncated muscle-specific isoforms of ankyrin 1 resulting fromusage of an alternate promoter have also been identified. (provided by RefSeq)

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 286
Alternate Names
  • SPH2
  • Ankyrin-R
  • ANK-1
  • ankyrin-R
  • ANK
  • ankyrin-1
  • Erythrocyte ankyrin
  • SPH1
  • ankyrin 1, erythrocytic

PTMs for Ankyrin 1

Learn more about PTMs related to Ankyrin 1.

Methylation
Hydroxylation
Acetylation

Bioinformatics Tool for Ankyrin 1

Discover related pathways, diseases and genes to Ankyrin 1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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