AMPK beta 1 Products

Description

The 5'-AMP-activated protein kinase (AMPK), a member of the SNF1 (sucrose non-fermentor) kinase family (1). AMPK is a heterotrimeric protein comprising alpha (63 kDa), beta (38 kDa) and gamma (38 kDa) subunits (2). The alpha subunit is the catalytic subunit, while beta and gamma are non-catalytic subunits, although they have been found to interact with the active subunit in liver. AMPK regulates fatty acid and sterol synthesis by phosphorylation of acetyl-CoA as well as cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase (3). AMPK beta-1 mediates the association of the AMPK heterotrimeric complex in vitro (2). Two isoforms have been found and the difference in expression patterns indicates tissue-specific roles for these isoforms (4).

Bioinformatics

Entrez	19079 Mouse 5564 Human 83803 Rat
Uniprot	AAH01007 Human AAH17671 Human AAKB_HUMAN Human NM_006253 Human NP_006244.2 Human Q9Y478 Human
Product By Gene ID	5564
Alternate Names	5'-AMP-activated protein kinase beta-1 subunit AMP-activated protein kinase beta subunit AMPK beta -1 chain AMPK beta 1,5'-AMP-activated protein kinase subunit beta-1 AMPK subunit beta-1 AMPK AMPKb HAMPKb MGC17785 protein kinase, AMP-activated, beta 1 non-catalytic subunit protein kinase, AMP-activated, noncatalytic, beta-1

Research Areas for AMPK beta 1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Hypoxia
mTOR Pathway
Phospho-Specific