AMBRA1 Products

Description

This antibody recognises human Activating molecule in beclin-1-regulated autophagy (AMBRA1), also known as WDR94. AMBRA1 is involved in the regulation of autophagy. Research indicates that it controls protein turnover during neuronal development and in regulating normal cell survival and proliferation. At least 5 isoforms of AMBRA have been identified.

Bioinformatics

Entrez	55626 Human
Uniprot	Q9C0C7 Human
Product By Gene ID	55626
Alternate Names	activating molecule in BECN1-regulated autophagy protein 1 autophagy/beclin-1 regulator 1 DCAF3 DDB1 and CUL4 associated factor 3 FLJ20294 KIAA1736activating molecule in beclin-1-regulated autophagy MGC33725 WD repeat domain 94 WDR94

Research Areas for AMBRA1

Find related products by research area and learn more about each of the different research areas below.

Autophagy

Related AMBRA1 Blog Posts

Check out the latest blog posts on AMBRA1.

Optogenetic Control of Mitophagy: AMBRA1 based mitophagy switch By Christina Towers, PhD Mitophagy in the BrainSelective autophagic degradation of damaged mitochondria, known as mitophagy, has been described as a cyto-protective process. Accordingly, defects in mitophagy h...    Read more.

Animal Models to Study Autophagy By Christina Towers, PhD What is autophagy?Autophagy is the catabolic process that degrades cytoplasmic material via the lysosome. The process of macroautophagy was originally characterized in yeast, where the...    Read more.

Beclin 2, a mammal-specific homolog of Beclin 1 with unique functional similarities and differences Beclin 2 (BECN2) is also called Beclin-1-like protein 1/ BECN1P1 and it was recently identified by He et al 2013 as a mammal-specific homolog of the evolutionarily conserved protein Beclin 1 which is well established for its role in the regulation ...    Read more.

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