Adrenomedullin R/ADMR/GPR182 Products

Antibodies
Adrenomedullin R/ADMR/GPR182 ...
Adrenomedullin R/ADMR/GPR182 Antibody
NBP1-90231
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Adrenomedullin R/ADMR/GPR182 ...
Adrenomedullin R/ADMR/GPR182 Antibody
NLS4048
Species: Hu
Applications: WB, IHC-P, ICC
Host: Rabbit Polyclonal
Adrenomedullin R/ADMR/GPR182 ...
Adrenomedullin R/ADMR/GPR182 Antibody
NBP1-02384
Species: Hu, Mk
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
Adrenomedullin R/ADMR/GPR182 ...
Adrenomedullin R/ADMR/GPR182 Overe...
NBL1-11268
Applications: WB
Proteins
Recombinant Human Adrenomedul ...
Recombinant Human Adrenomedullin R...
H00011318-Q01
Species: Hu
Applications: WB, ELISA, PA
Adrenomedullin R/ADMR/GPR182 ...
Adrenomedullin R/ADMR/GPR182 Recom...
NBP1-90231PEP
Species: Hu
Applications: AC
Recombinant Human Adrenomedul ...
Recombinant Human Adrenomedullin R...
H00011318-G01
Species: Hu
RNAi
Adrenomedullin R/ADMR/GPR182 ...
Adrenomedullin R/ADMR/GPR182 RNAi
H00011318-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

G Protein-Coupled Receptor L1/G10D has been suggested to be an Adrenomedullin Receptor. Originally cloned from rats and later from humans, L1/G10D does not to bind adrenomedullin or display functional cAMP response to adrenomedullin (reviewed in Poyner et al. 2002). The initial experimental results, which demonstrated high-affinity binding and increased levels of cAMP in COS cells that were transfected with L1/G10D and treated with adrenomedullin, could not be reproduced by other laboratories (Kapas et al. 1995). It is now known that the functional adrenomedullin receptor is a heterodimeric complex composed of calcitonin receptor-like receptor (CRLR) and receptor activity modifying proteins (RAMPs) (McLatchie et al. 1998). L1/G10D therefore should be considered an Orphan A receptor. L1/G10D expression has been reported in adrenal gland, bone marrow, brain, heart, kidney, liver, lung, lymph node, pancreas, skeletal muscle, small intestine, spleen, stomach, testis, and thyroid. ESTs have been isolated from kidney, liver/spleen, fetal lung/testis/B-cell, and melanocyte/uterus/fetal heart libraries.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 11318
Alternate Names
  • ADMR
  • gamrh
  • hrhAMR
  • G-protein coupled receptor 182
  • adrenomedullin receptor
  • MGC34399
  • G10D
  • AMR
  • AM-R
  • G protein-coupled receptor 182,7TMR

Research Areas for Adrenomedullin R/ADMR/GPR182

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GPCR

Bioinformatics Tool for Adrenomedullin R/ADMR/GPR182

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