ADK Products

Antibodies
ADK Antibody
ADK Antibody
NBP2-15291
Species: Hu, Mu, Rt, Bovine, Monkey
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
ADK Antibody
ADK Antibody
NBP1-90197
Species: Hu, Mu, Rt, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
ADK Overexpression Lysate (Na ...
ADK Overexpression Lysate (Native)
NBP2-10955
Applications: WB
Proteins
ADK Recombinant Protein
ADK Recombinant Protein
H00000132-P01
Species: Hu
Applications: WB, ELISA, PA
ADK Partial Recombinant Prote ...
ADK Partial Recombinant Protein
H00000132-Q01
Species: Hu
Applications: WB, ELISA, PA
ADK Recombinant Protein Antig ...
ADK Recombinant Protein Antigen
NBP1-90197PEP
Species: Hu
Applications: AC
RNAi
ADK RNAi
ADK RNAi
H00000132-R06
Species: Hu
ADK RNAi
ADK RNAi
H00000132-R05
Species: Hu

Description

Adenosine kinase (ATP:adenosine 5 prime phosphotransferase) is an abundant enzyme in mammalian tissues that catalyzes the transfer of the gamma phosphate from ATP to adenosine, thereby serving as a potentially important regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of ADK could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as antiinflammatory agents. The encoded protein does not present any sequence similarities to other well characterized mammalian nucleoside kinases. In contrast, 2 regions were identified with significant sequence identity to microbial ribokinase and fructokinases and a bacterial inosine/guanosine kinase. Thus, ADK is a structurally distinct mammalian nucleoside kinase that appears to be akin to sugar kinases of microbial origin.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 132
Alternate Names
  • EC 2.7.1
  • EC 2.7.1.20
  • AKAdenosine 5'-phosphotransferase
  • adenosine kinase

Research Areas for ADK

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism

PTMs for ADK

Learn more about PTMs related to ADK.

Phosphorylation
Methylation
Demethylation
Reduction
Cleavage

Bioinformatics Tool for ADK

Discover related pathways, diseases and genes to ADK. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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