Adenylate Cyclase 1 Products

Adenylate Cyclase 1 Antibody
Adenylate Cyclase 1 Antibody
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Adenylate Cyclase 1 Overexpre ...
Adenylate Cyclase 1 Overexpression...
Applications: WB
Adenylate Cyclase 1 RNAi
Adenylate Cyclase 1 RNAi
Species: Hu


Adenylyl cyclases function to convert ATP to cyclic AMP in response to activation by a variety of hormones, neurotransmitters and other regulatory molecules. Cyclic AMP, in turn, activates several other target molecules to control a broad range of diverse phenomena such as metabolism, gene transcription and memory. Adenylyl cyclases respond to receptor-initiated signals, mediated by the Gs and Gi heterotrimeric G proteins. The binding of an agonist to a Gs-coupled receptor catalyzes the exchange of GDP (bound to Galpha s) for GTP, the dissociation of GTP-Galpha s from Gbetagamma and Galpha s)-mediated activation of adenylyl cyclase. Adenylyl cyclases type I (AC I) and III (AC III) have distinct staining within the cell nucleus of rat brain sensory neurons. AC I is expressed in myenteric ganglia as two bands of 160 kDa and 185 kDa by SDS-PAGE. Ca2+ stimulation of AC I and AC III is mediated by calmodulin. Protein associated with Myc (PAM) is a very potent inhibitor of AC I. A decrease in endogenous PAM levels in HeLa cells modulate both basal and agonist stimulated cAMP accumulation.


Entrez Human
Uniprot Human
Product By Gene ID 107
Alternate Names
  • adenylate cyclase type 1
  • ATP pyrophosphate-lyase 1
  • adenyl cyclase
  • Adenylyl cyclase 1
  • 3'-5'-cyclic AMP synthetase
  • Adenylate cyclase type I
  • EC
  • AC1
  • Ca(2+)/calmodulin-activated adenylyl cyclase
  • adenylate cyclase 1 (brain)

Pathways for Adenylate Cyclase 1

View related products by pathway and learn more about each of the pathways below.

Circadian Rhythm
Cellular Localization
Camp-mediated Signaling
Long-term Memory
Regulation Of Gene Expression
Glomerular Filtration
Rna Splicing

Research Areas for Adenylate Cyclase 1

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism

Bioinformatics Tool for Adenylate Cyclase 1

Discover related pathways, diseases and genes to Adenylate Cyclase 1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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