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ADAM29, or Disintegrin and metalloproteinase domain-containing protein29, contains an alpha 93 kDa isoform, a beta 87 kDa isoform, and a gamma 90 kDa isoform, and is involved in the processes of fertilization and spermatogenesis. Current research is being conducted on the protein's relation to a variety of cancers, including chronic lymphocytic leukemia, lymphocytic leukemia, and melanoma. ADAM29 has been linked to the processes of proteolysis and spermatogenesis, in which it interacts with ABI2.