Species: Hu, Mu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Species: Mu, Rt
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, PA, AP
Species: Hu
Applications: WB, ELISA, PA, AP
Species: Hu
Applications: AC
Description
ACTL7B is encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known.
Bioinformatics
| Entrez |
Human
Mouse
Rat
|
| Uniprot |
Human
Human
Human
Human
Rat
|
| Product By Gene ID |
10880 |
| Alternate Names |
- Actin-like-7-beta
- actin-like-7-beta
- actin-like protein 7B
- actin-like 7-beta
- Tact1
- actin-like 7B
|
Pathways for ACTL7B
View related products by pathway and learn more about each of the pathways below.
MethylationDemethylation
Research Areas for ACTL7B
Find related products by research area and learn more about each of the different research areas below.
Chromatin Research
PTMs for ACTL7B
Learn more about PTMs related to ACTL7B.
Methylation
Bioinformatics Tool for ACTL7B
Discover related pathways, diseases and genes to ACTL7B. Need help? Read the
Bioinformatics Tool Guide for instructions on using this tool.
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