ACCN2 Products

Antibodies
ACCN2 Antibody (S271-44)
ACCN2 Antibody (S271-44)
NBP2-22409
Species: Mu
Applications: WB, ICC/IF, IHC
Host: Mouse Monoclonal
ACCN2 Antibody
ACCN2 Antibody
NBP2-42507
Species: Mu
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
ACCN2 Antibody
ACCN2 Antibody
NBP2-15240
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
ACCN2 Overexpression Lysate ( ...
ACCN2 Overexpression Lysate (Native)
NBL1-07231
Applications: WB
ACCN2 Overexpression Lysate ( ...
ACCN2 Overexpression Lysate (Native)
NBP2-08232
Applications: WB
Proteins
ACCN2 Recombinant Protein
ACCN2 Recombinant Protein
H00000041-P01
Species: Hu
Applications: WB, ELISA, PA
ACCN2 Partial Recombinant Pro ...
ACCN2 Partial Recombinant Protein
H00000041-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
ACCN2 RNAi
ACCN2 RNAi
H00000041-R02
Species: Hu
Applications: RNAi, RNAi SP
ACCN2 RNAi
ACCN2 RNAi
H00000041-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

ACCN2 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is expressed in most if not all brain neurons, and it may be an ion channel subunit; however, its function as an ion channel remains unknown.; FUNCTION: Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Ca(2+), Li(+) and K(+).; SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Note=Localizes in synaptosomes at dendritic synapses of neurons.; TISSUE SPECIFICITY: Expressed in dorsal root ganglia (DRG) and sciatic nerve (at protein level). Widely distributed throughout the brain. Expressed in olfactory bulb, neo and allocortical regions, dentate granule cells, pyramidal cells of CA1-CA3 subfields of the hippocampal formation, habenula, basolateral amygdaloid nuclei, and in the Purkinje and granule cells of the cerebellum. Diffusely detected over most other regions of the basal ganglia, including thalamic nuclei, substantia nigra, striatum and globus pallidus, hypothalamus, midbrain, pons, medulla and choroid plexus. Isoform 3 is expressed only in dorsal root ganglion while isoform 1 is expressed in DRG, spinal chord, trigeminal ganglia and the trigeminal mesencephalic nucleus.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 41
Alternate Names
  • BNAC2
  • Brain sodium channel 2
  • Cation channel, amiloride-sensitive, neuronal, 2
  • Acid-sensing ion channel 1
  • acid-sensing ion channel 1a protein
  • hBNaC2
  • BNaC2ACCN2 variant 3
  • ASIC1ASIC1A
  • ASIC
  • amiloride-sensitive cation channel 2, neuronal

PTMs for ACCN2

Learn more about PTMs related to ACCN2.

Phosphorylation
Cleavage
Biotinylation
Dephosphorylation

Bioinformatics Tool for ACCN2

Discover related pathways, diseases and genes to ACCN2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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