beta-III Tubulin Products

Description

Beta-III Tubulin is abundant in the central and peripheral nervous systems where it is prominently expressed during fetal and postnatal development. Beta III Tubulin is often referred to as TUJ1 because Tuj-1 is the clone name of the original monoclonal antibody. The Tuj1 clone is such a popular neuronal marker that Tuj-1 is now used as a synonym for beta III tubulin. The distribution of Tubulin Beta 3 is neuron-associated, exhibiting distinct temporospatial gradients according to the regional neuroepithelia of origin. However, transient expression of the Tubulin Beta 3 protein is also present in the subventricular zones of the CNS comprising putative neuronal- and/or glial precursor cells, as well as in Kulchitsky neuroendocrine cells of the fetal respiratory epithelium. This temporally restricted, potentially non-neuronal expression may have implications in the identification of presumptive neurons derived from embryonic stem cells. Mutation on beta-tubulin has been linked to anti-cancer drug resistance in lung cancers.

Bioinformatics

Entrez	10381 Human 22142 Mouse 22152 Mouse 246118 Rat 64158 Rat
Uniprot	AAH00748 Human NM_006086 Human NP_006077.2 Human Q13509 Human Q4QRB4 Rat
Product By Gene ID	10381
Alternate Names	beta-4 TUBB4 CFEOM3A tubulin beta-3 chain Tubulin beta-4 chain Tubulin beta-III tubulin, beta 3 TUJ1 antigen TUJ-1 antigen

Research Areas for beta-III Tubulin

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Cellular Markers
Cytoskeleton Markers
Neuroscience
Phospho-Specific

Related beta-III Tubulin Blog Posts

Check out the latest blog posts on beta-III Tubulin.

Beta Tubulin III and neurogenesis Beta tubulin III, also known as Tuj-1, is a class III member of the beta tubulin protein family. Beta tubulins are one of two structural components that form our microtubule network. While general tubulins play a role in a wide range of cellular pr...    Read more.

Beta III tubulin The Beta III tubulin protein is abundantly present in both the central and peripheral nervous systems (CNS and PNS), where it is predominantly expressed during fetal and postnatal development. In cerebellar and sympathoadrenal neurogenesis, Beta III d...    Read more.

Successful Transplantation of Friedreich Ataxia Induced Pluripotent Stem Cell (iPSC)-Derived Sensory Neurons in Dorsal Root Ganglia of Adult Rodents Jamshed Arslan, Pharm D, PhD The dorsal root ganglia (DRG) are a collection of cell bodies of sensory nerves carrying sensory information – including nociception, mechanoreception and proprioception – from periphera...    Read more.

Read more beta-III Tubulin related blogs.