beta Adducin Products

Description

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta and gamma). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-actin junction of the membrane skeleton. The cortical actin cytoskeletal network is lost during apoptosis and adducins are central in the cortical actin network organization. Adducin alpha is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin alpha and Adducin gamma is ubiquitous in contrast to the restricted expression of Adducin beta. Adducin beta is expressed at high levels in brain and hematopoietic tissues, such as bone marrow in humans, and spleen in mice.

Bioinformatics

Entrez	11519 Mouse 119 Human 24171 Rat
Uniprot	AAH65525.1 Human NM_001617 Human NM_017488 Human NP_059516 Human P35612 Human
Product By Gene ID	119
Alternate Names	ADDBErythrocyte adducin subunit beta adducin 2 (beta) beta adducin beta-adducin

Research Areas for beta Adducin

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Stem Cell Markers