MMP24 (Matrix metalloproteinase-24, matrix metalloproteinase-25, MT5-MMP)

MMP24 is an extracellular matrix (ECM) degradative peptidase enzyme that is a member of the large family of matrix metalloproteinases (MMP). Each MMP has a different substrate specificity, and the aberrant or derailed expression of these is strongly correlated with unregulated events such as tumor invasion, metastasis, angiogenesis, and arthritis. This is in contrast to the tightly controlled normal physiological processes such as tissue remodeling, reproduction, rebuilding, and embryonic development. Deregulation often occurs through the loss of negative checks.