TCF4

Beta Catenin is a cytosolic, 88 kDa intracellular protein that tightly associates with cell surface cadherin glycoproteins. It is one member of the catenin family that includes alpha Catenin, beta Catenin, and gamma Catenin. Colocalization studies using beta-catenin antibodies demonstrate that beta-catenin is a crucial link between cytoplasmic, cytoskeletal actin and transmembrane cadherin for tight cell-to-cell adhesion (1,2).