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Glucose

Deficiency of GluT1 leads to neurological problems while excess is involved in cancers

Immunohistochemical staining of formalin fixed paraffin embedded tissue of human placenta with rabbit polyclonal Glut1 antibody and staining developed using HRP-DAB with hematoxylin counterstaining.

By Jamshed Arslan, Pharm. D., PhD.

Tags: 
Glucose
GLUT1
galactose
epilepsy
GluT1-deficiency syndrome (GDS)
SLC2A1
Cancer
tubulin 4
glioblastoma
ChREBP
GluT2
Hepatocellular Carcinoma
Jamshed Arslan

O-GlcNAc, Glucose Deprivation and Cancer

O-linked beta-N-acetylglucosamine (O-GlcNAc) is a sugar attachment to serine or threonine hydroxyl moieties on nuclear and cytoplasmic proteins. O-GlcNAc modified proteins are generally either cytoplasmic or nuclear proteins, and unlike asparagine-linked or mucin-type O-glycosylation, O-GlcNAc is not further processed into a complex oligosaccharide.

Tags: 
ATP
Glucose
O-GlcNAc
O-GlcNAc antibody