Cystic Fibrosis Transmembrane Regulator

The ABC (ATP-binding cassette) transporters are a superfamily of transmembrane proteins which play an essential role in membrane transport in both prokaryotes and eukaryotes. In humans, ABC transporters have been implicated in many conditions. For example, ABCA1 antibody research has shown mutations in the ABCA1 gene can cause Tangier disease, while the ABCB family causes multiple drug resistance.