SM047: A Powerful Ovarian Carcinoma Marker

The SM047 antibody is an IgM monoclonal antibody that was developed by McCluggage's group at the UK Royal Group of Hospitals and recognizes a multivalent antigen from ovarian carcinoma (OvC) cells (1). Early studies indicate that the epitope is specifically expressed in the adenocarcinoma glycocalyx, and is most strongly expressed in serous OvC subtypes.