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AKAP8

AKAP95/AKAP8 Orchestrates and Synchronizes Cellular Events

A-kinase anchor proteins (AKAPs), such as AKAP95/AKAP8, are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA). AKAPs orchestrate and synchronize cellular events by tethering the cAMP-dependent PKA and other signaling enzymes to organelles and membranes. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis (1).

Tags: 
AKAP8
AKAP95
AKAP95/AKAP8
AKAP95/AKAP8 antibody
cAMP
cAMP antibody
cell cycle
cyclic AMP
PKA
PKA-RI
PKA-RII
protein kinase A
scaffold proteins