Abeta 42 Products

Description

The amyloid beta peptide (A beta) is the main component of amyloid deposits found in the brain of patients afflicted with Alzheimer's disease. Brain to blood transport is believed to be a major determinant of the amount of amyloid beta protein (AbetaP) found in brain. Chronic brain hypoperfusion (CBH) initiates spatial memory loss in aging rats thus mimicking human mild cognitive impairment (MCI) and also increases A beta in the hippocampus. The memory and amyloid changes are preceded by NO upregulation in the hippocampus. These preliminary findings may be important in understanding, at least in part, the molecular mechanisms that precede memory impairment during chronic brain ischemia and as such, the pre-clinical stage leading to Alzheimer's disease.

Bioinformatics

Product By Gene ID	351
Alternate Names	Amyloid beta 42 Beta-amyloid protein 42

Research Areas for Abeta 42

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Cell Cycle and Replication

Related Abeta 42 Blog Posts

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Using Amyloid beta peptides in Alzheimer's Disease Immunization Amyloid beta (AB) peptide has a central role in the neurodegeneration of Alzheimer's disease (AD). Immunization of AD transgenic mice with AB-42 peptide reduces both the spatial memory impairments and AD-like neuropathologic changes.Therapeutic im...    Read more.

Amyloid beta and Methionine Sulfoxide Related to Abeta 42 Antibody and Abeta 40 Antibody By Eric NeeleyAlzheimer's disease is a devastating neurodegenerative illness characterized by the formation of plaques, tangles, and eventually synaptic loss. Amyloid beta (A beta ) is the processed form of the Amyloid precursor protein (APP), and whose ...    Read more.

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