Rheb Products

Description

Ras homolog enriched in brain (RheB) is a member of the Ras superfamily that was originally identified as an immediate-early gene in brain but is also widely expressed in other tissues. RheB encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. Rheb is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. Recombinant human RheB protein, fused to T7-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Bioinformatics

Product By Gene ID	6009
Alternate Names	GTP-binding protein Rheb MGC111559 Ras homolog enriched in brainRHEB2Ras homolog enriched in brain 2 Rheb Rheb2

Research Areas for Rheb

Find related products by research area and learn more about each of the different research areas below.

Cancer
mTOR Pathway
Signal Transduction

Related Rheb Blog Posts

Check out the latest blog posts on Rheb.

TSC1 - a negative regulator of mTOR signaling TSC1 is a tumor suppressor gene that encodes a 130 kDa protein called hamartin. TSC1 was first identified as an oncogenic driver of Tuberous Sclerosis, a condition characterized by numerous benign tumors of the skin, brain, heart, and lungs. A mut...    Read more.

mTOR - a central regulator of cell metabolism The mammalian target of rapamycin (mTOR) signaling pathway allows cells to monitor environmental signals like nutrient availability and oxygen levels. mTOR is a phosphoinositide 3-kinase (PI3K)-related protein that assembles into large protein comp...    Read more.

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