10549-CV) binds Recombinant Human ACE-2 (933-ZN) in a functional ELISA. The binding activity is approximately 4-fold greater than a top competitor’s Spike protein (full ectodomain)." class="big_lightbox"> 10549-CV) binds Recombinant Human ACE-2 (933-ZN) in a functional ELISA. The binding activity is approximately 4-fold greater than a top competitor’s Spike protein (full ectodomain)." alt="R&D Systems Recombinant SARS-CoV-2 Spike (10549-CV) binds Recombinant Human ACE-2 (933-ZN) in a functional ELISA. The binding activity is approximately 4-fold greater than a top competitor’s Spike protein (full ectodomain)." class="big_thumb" />

10549-CV) was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by Coomassie® Blue staining, showing bands at 144-175 kDa." class="big_lightbox"> 10549-CV) was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by Coomassie® Blue staining, showing bands at 144-175 kDa." class="big_thumb" />

933-ZN) was measured at a concentration range between 0.37 nM and 93.5 nM. The double-referenced sensorgram was fit to a 1:1 binding model to determine the binding kinetics and affinity, with an affinity constant of KD=1.720 nM." class="big_lightbox"> 933-ZN) was measured at a concentration range between 0.37 nM and 93.5 nM. The double-referenced sensorgram was fit to a 1:1 binding model to determine the binding kinetics and affinity, with an affinity constant of KD=1.720 nM." class="big_thumb" />

10549-CV) or a competitor’s Spike protein were run under reducing or non-reducing conditions and visualized by silver staining. The R&D Systems Spike protein runs as a single band compared to the competition." class="big_lightbox"> 10549-CV) or a competitor’s Spike protein were run under reducing or non-reducing conditions and visualized by silver staining. The R&D Systems Spike protein runs as a single band compared to the competition." class="big_thumb" />

IC050A), which does not stain the cells in the absence of recombinant protein (B)." class="big_lightbox"> IC050A), which does not stain the cells in the absence of recombinant protein (B)." class="big_thumb" />

933-ZN) in a functional ELISA." class="big_lightbox"> 933-ZN) in a functional ELISA." alt="Recombinant SARS-CoV-2 Spike B.1.617.2 (GCN4-IZ) His-tag (Catalog # 10878-CV) binds Recombinant Human ACE-2 His-tag (933-ZN) in a functional ELISA." class="big_thumb" />

933-ZN) was measured at a concentration range between 0.046 nM and 47.2 nM. The double-referenced sensorgram was fit to a 1:1 binding model to determine the binding kinetics and affinity, with an affinity constant of KD=1.29 nM." class="big_lightbox"> 933-ZN) was measured at a concentration range between 0.046 nM and 47.2 nM. The double-referenced sensorgram was fit to a 1:1 binding model to determine the binding kinetics and affinity, with an affinity constant of KD=1.29 nM." class="big_thumb" />

933-ZN) in a functional ELISA." class="big_lightbox"> 933-ZN) in a functional ELISA." alt="Recombinant SARS-CoV-2 B.1.1.529 Spike His-tag (Catalog # 11060-CV) binds Recombinant Human ACE-2 His-tag (933-ZN) in a functional ELISA." class="big_thumb" />

933-ZN) was measured at a concentration range between 0.021 nM and 53.1 nM. The double-referenced sensorgram was fit to a 1:1 binding model to determine the binding kinetics and affinity, with an affinity constant of K_d=3.63 nM." class="big_lightbox"> 933-ZN) was measured at a concentration range between 0.021 nM and 53.1 nM. The double-referenced sensorgram was fit to a 1:1 binding model to determine the binding kinetics and affinity, with an affinity constant of K_d=3.63 nM." class="big_thumb" />

933-ZN) in a functional ELISA." class="big_lightbox"> 933-ZN) in a functional ELISA." alt="Recombinant SARS-CoV-2 B.1.351 Spike (GCN4-IZ) His-tag (Catalog # 10786-CV) binds Recombinant Human ACE-2 His-tag (933-ZN) in a functional ELISA." class="big_thumb" />

933-ZN) was measured at a concentration range between 0.046 nM and 47.2 nM. The double-referenced sensorgram was fit to a 1:1 binding model to determine the binding kinetics and affinity, with an affinity constant of KD=1.272 nM." class="big_lightbox"> 933-ZN) was measured at a concentration range between 0.046 nM and 47.2 nM. The double-referenced sensorgram was fit to a 1:1 binding model to determine the binding kinetics and affinity, with an affinity constant of KD=1.272 nM." class="big_thumb" />

933-ZN) in a functional ELISA." class="big_lightbox"> 933-ZN) in a functional ELISA." class="big_thumb" />

933-ZN) was measured at a concentration range between 0.37 nM and 94.3 nM. The double-referenced sensorgram was fit to a 1:1 binding model to determine the binding kinetics and affinity, with an affinity constant of KD=2.580 nM. " class="big_lightbox"> 933-ZN) was measured at a concentration range between 0.37 nM and 94.3 nM. The double-referenced sensorgram was fit to a 1:1 binding model to determine the binding kinetics and affinity, with an affinity constant of KD=2.580 nM. " class="big_thumb" />

933-ZN) in a functional ELISA." class="big_lightbox"> 933-ZN) in a functional ELISA." alt="Recombinant SARS-CoV-2 B.1.1.7 Spike (GCN4-IZ) His-tag (Catalog # 10796-CV) binds Recombinant Human ACE-2 His-tag (933-ZN) in a functional ELISA." class="big_thumb" />

933-ZN) was measured at a concentration range between 0.046 nM and 47.2 nM. The double-referenced sensorgram was fit to a 1:1 binding model to determine the binding kinetics and affinity, with an affinity constant of KD=0.6131 nM." class="big_lightbox"> 933-ZN) was measured at a concentration range between 0.046 nM and 47.2 nM. The double-referenced sensorgram was fit to a 1:1 binding model to determine the binding kinetics and affinity, with an affinity constant of KD=0.6131 nM." class="big_thumb" />

933-ZN) in a functional ELISA." class="big_lightbox"> 933-ZN) in a functional ELISA." alt="Recombinant SARS-CoV-2 P.1 Spike (GCN4-IZ) His-tag (Catalog # 10795-CV) binds Recombinant Human ACE-2 His-tag (933-ZN) in a functional ELISA." class="big_thumb" />

933-ZN) in a functional ELISA." class="big_lightbox"> 933-ZN) in a functional ELISA." alt="Recombinant SARS-CoV Spike His-tag (Catalog # 10683-CV) binds Recombinant Human ACE-2 His-tag (933-ZN) in a functional ELISA." class="big_thumb" />

933-ZN) in a functional ELISA." class="big_lightbox"> 933-ZN) in a functional ELISA." alt="Recombinant SARS-CoV-2 B.1.617.1 Spike (GCN4-IZ) His-tag (Catalog # 10861-CV) binds Recombinant Human ACE-2 His-tag (933-ZN) in a functional ELISA." class="big_thumb" />

933-ZN) was measured at a concentration range between 0.046 nM and 47.2 nM. The double-referenced sensorgram was fit to a 1:1 binding model to determine the binding kinetics and affinity, with an affinity constant of KD=1.819 nM." class="big_lightbox"> 933-ZN) was measured at a concentration range between 0.046 nM and 47.2 nM. The double-referenced sensorgram was fit to a 1:1 binding model to determine the binding kinetics and affinity, with an affinity constant of KD=1.819 nM." class="big_thumb" />

933-ZN) in a functional ELISA." class="big_lightbox"> 933-ZN) in a functional ELISA." alt="Recombinant SARS-CoV-2 B.1.1.7 Spike His-tag (Catalog # 10748-CV) binds Recombinant Human ACE-2 His-tag (933-ZN) in a functional ELISA." class="big_thumb" />

933-ZN) was measured at a concentration range between 0.18 nM and 94.3 nM. The double-referenced sensorgram was fit to a 1:1 binding model to determine the binding kinetics and affinity, with an affinity constant of KD=1.185 nM." class="big_lightbox"> 933-ZN) was measured at a concentration range between 0.18 nM and 94.3 nM. The double-referenced sensorgram was fit to a 1:1 binding model to determine the binding kinetics and affinity, with an affinity constant of KD=1.185 nM." class="big_thumb" />

10544-ZN) in a functional ELISA." class="big_lightbox"> 10544-ZN) in a functional ELISA." alt="Recombinant SARS-CoV-2 BA.4/BA.5 Spike His-tag Protein (Catalog # 11232-CV) binds Recombinant Human ACE-2 Fc Chimera (10544-ZN) in a functional ELISA." class="big_thumb" />

933-ZN) in a functional ELISA." class="big_lightbox"> 933-ZN) in a functional ELISA." alt="Recombinant SARS-CoV-2 A.23.1 Spike (GCN4-IZ) His-tag (Catalog # 10860-CV) binds Recombinant Human ACE-2 His-tag (933-ZN) in a functional ELISA." class="big_thumb" />

933-ZN) was measured at a concentration range between 0.046 nM and 47.2 nM. The double-referenced sensorgram was fit to a 1:1 binding model to determine the binding kinetics and affinity, with an affinity constant of KD=2.29 nM." class="big_lightbox"> 933-ZN) was measured at a concentration range between 0.046 nM and 47.2 nM. The double-referenced sensorgram was fit to a 1:1 binding model to determine the binding kinetics and affinity, with an affinity constant of KD=2.29 nM." class="big_thumb" />