XAGE1D Antibody

Product Discontinued

XAGE1D Antibody Summary

• Immunogen: Peptide with sequence CPEAGEEQPQV corresponding to C-Terminus according to NP_065144, CAC38108, NP_597674.
• Specificity: This antibody is expected to recognise the isoforms represented by NP_065144; CAC38108; NP_597674.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: XAGE1D
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:2000
• Application Notes: WB: Preliminary experiments in human testis lysates and in lysates of different human epithelial cell lines gave no specific signal but low background.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for XAGE1D Antibody

• cancer/testis associated protein
• CT12.1C
• CTP9
• G antigen family D member 2
• member 1c
• X antigen family, member 1C
• XAGE1

Background

XAGE1 is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. XAGE1 is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. XAGE1 contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of XAGE1 generates 3 transcript variants, and one of which includes 2 transcripts generated from alternate transcription initiation sites.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for XAGE1D Antibody (NB300-816)(1)

Publication using NB300-816

• Liu XF, Helman LJ, Yeung C et al. XAGE-1, a new gene that is frequently expressed in Ewing's sarcoma. Cancer Res 2000-09-01 [PMID: 10987281]

Bioinformatics

• Gene Symbol: XAGE1D
• Entrez:
  • 9503(Human)
• Uniprot:
  • NP_065144(Human)