Tryptase beta-1/MCP-7/Mcpt7 Antibody (263019) [Alexa Fluor® 647]

• Reactivity: Mu
• Applications: WB
• Clone: 263019
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 647

Tryptase beta-1/MCP-7/Mcpt7 Antibody (263019) [Alexa Fluor® 647] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Tryptase β‑1/MCP‑7/Mcpt7
  Ile29-Phe273
  Accession # Q02844
• Specificity: Detects mouse Tryptase beta ‑1/MCP‑7/Mcpt7 in direct ELISAs and Western blots. In direct ELISAs, 100% cross‑reactivity with recombinant human (rh) Tryptase alpha and rhTryptase beta ‑2 is observed and no cross-reactivity with recombinant mouse MCPT-1 is ob
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Tryptase beta-1/MCP-7/Mcpt7 Antibody (263019) [Alexa Fluor® 647]

• Mast Cell Tryptase
• Mcp7
• MCP-7
• Mcpt7
• TPSB1
• TRYB1
• Tryptase beta1
• Tryptase beta-1

Background

Tryptase beta -1 is a serine protease with trypsin-like activity, which is sometimes also referred to as Mast Cell Protease 7 (MCP-7 or Mcpt7) (1). It is stored in the secretory granules of mouse mast cells (2). It exhibits anticoagulant activity due to its ability to degrade fibrinogen in the presence of the diverse array of protease inhibitors in plasma (3). The deduced amino acid (aa) sequence for mouse Tryptase beta -1 consists of a signal peptide (aa 1‑18), a pro region (aa 19‑28) and the mature chain (aa 29‑273).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.