TLR11 Antibody Blocking Peptide Summary
| Specificity |
This peptide is specific for NB100-56742 only. |
| Protein/Peptide Type |
Antibody Blocking Peptide |
| Gene |
TLR11 |
Applications/Dilutions
| Dilutions |
|
| Application Notes |
This peptide is useful as a blocking peptide for NB100-56742. For further blocking peptide related protocol, click here. |
Packaging, Storage & Formulations
| Storage |
Store at -80C. Avoid freeze-thaw cycles. |
| Buffer |
Peptide dissolved in dH20. Contains no BSA. |
| Preservative |
No Preservative |
| Concentration |
1 mg/ml |
Alternate Names for TLR11 Antibody Blocking Peptide
Background
Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are
guaranteed for 3 months from date of receipt.
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