TeNT Light Chain/Tetanus Toxin Antibody (TetE3) - BSA Free

• Reactivity: Ba
• Applications: WB, ELISA
• Clone: TetE3
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free

TeNT Light Chain/Tetanus Toxin Antibody (TetE3) - BSA Free Summary

• Immunogen: Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with supernatant from C. tetani.
• Specificity: TeNT Light Chain/Tetanus Toxin Antibody (TetE3) has toxin neutralization activity (in vivo assay).
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: TETX
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:100-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS (pH 7.4)
• Preservative: 0.09% Sodium Azide
• Purity: Protein G purified

Alternate Names for TeNT Light Chain/Tetanus Toxin Antibody (TetE3) - BSA Free

• TeNT Light Chain
• TeNT-LC
• Tentoxylysin
• Tetanus toxin chain H
• Tetanus toxin chain L
• Tetanus toxin heavy chain
• Tetanus toxin light chain
• tetX

Background

Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the 76-Gln-|-Phe-77 bond of synaptobrevin-2. The precursor polypeptide is subsequently cleaved to yield subchains L and H. These remain linked by a disulfide bridge and are non-toxic after separation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TETX