| Reactivity | HuSpecies Glossary |
| Applications | WB |
| Clone | 766842 |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugate | Alexa Fluor 750 |
| Immunogen | Chinese hamster ovary cell line CHO-derived recombinant human Tenascin XB2 Met1-Tyr673 Accession # AAH33740 |
| Specificity | Detects human Tenascin XB2 in ELISAs and Western blots. Also detects Tenascin X in Western blots. In direct ELISAs, no cross-reactivity with recombinant human Tenascin R is observed. |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Host | Mouse |
| Purity | Protein A or G purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Storage | Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied |
| Buffer | Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide |
| Purity | Protein A or G purified |
Tenascin XB2 (TN-XB2; also TN-XB-Short/S and tenascin-X isoform 2) is a 73-75 kDa member of the tenascin family of extracellular matrix molecules. It is expressed by adrenal gland, and represents the use of an intronic promoter that is tied to an internal start site within the TN-XB gene. A duplication of the TN-XB2 region has created a gene called TN-XA that codes for the same ORF but is not translated. Although TN-XB2 has been reported to bind to tropoelastin, plus collagens I, III and V, other studies using soluble fragments of TN-XB report only tropoelastin interaction. Human TN-XB2 is 673 amino acids (aa) in length. It contains four fibronectin type III repeats (aa 82-442), and one C-terminal fibrinogen-like globular region (aa 449-664). Antibodies to TN-XB2 recognize full-length 465 kDA Tenascin X (TN-XB), 75 kDa and 140-150 kDa C-terminal fragments. Although human TN-XB2 shares 84% aa identity with full-length mouse TN-XB in its C-terminus, there does not appear to be an equivalent alternative start site in the mouse gene.
Secondary Antibodies |
Isotype Controls |
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