Recombinant SARS-CoV-2 Spike S2 (ECD) Protein


SDS-Page: Recombinant Virus SARS-CoV-2 Spike S2 Protein [NBP2-92990] - Recombinant Virus SARS-CoV-2 Spike S2 ECD Protein with His tag was determined by SDS-PAGE with Coomassie Blue, showing a band at 70 kDa.

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Recombinant SARS-CoV-2 Spike S2 (ECD) Protein Summary

Recombinant SARS-CoV-2 Spike S2 ECD Protein is produced by Baculovirus-Insect Cells expression system. The target protein is expressed with sequence (Ser686-Pro1213) of SARS-CoV-2 Spike S2 ECD (Accession #YP_009724390.1) fused with a His tag at the C-terminus.
Protein/Peptide Type
Recombinant Protein
>90%, by SDS-PAGE
Endotoxin Note
< 1.0 EU/ug of the protein by LAL method.


Theoretical MW
58 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Store at -20 to -70C. Avoid freeze-thaw cycles.
Lyophilized from a 0.22 um filtered solution of sterile 20 mM PBS, 300 mM NaCl, 10% glycerol,pH 7.0.
No Preservative
>90%, by SDS-PAGE
Reconstitution Instructions
Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.


Store the lyophilized protein at -20 degrees C to -80 degrees C for long term. After reconstitution, the protein solution is stable at -20 degrees C for 3 months, at 2-8 degrees C for up to 1 week.

Alternate Names for Recombinant SARS-CoV-2 Spike S2 (ECD) Protein

  • COVID-19
  • S2 protein
  • SARS-CoV-2 Spike
  • Spike glycoprotein Subunit 2
  • Spike protein S2


It has recently been shown that SARS-CoV-2 (severe acute respiratory syndrome) is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness, such as the common cold, in humans. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The glycosilated spike protein (as well as the nucleocapsid protein) can be detected in infected cell culture supernatants with antisera from SARS-CoV-2 patients.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Array NBP2-92990

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