Recombinant SARS-CoV-2 Nucleocapsid Protein

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Product Details

Summary
Concentration
LYOPH

Order Details

Recombinant SARS-CoV-2 Nucleocapsid Protein Summary

Description
A full length recombinant protein with a C-Terminal His-tag and corresponding to the amino acids sequence of the SARS-COV-2 Nucleocapsid Protein

Source: E.coli

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Purity
>90% SDS-PAGE

Applications/Dilutions

Theoretical MW
48 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 10mM K2CO3 before Lyophilization.
Preservative
No Preservative
Concentration
LYOPH
Purity
>90% SDS-PAGE
Reconstitution Instructions
Reconstitute in sterile H2O.

Alternate Names for Recombinant SARS-CoV-2 Nucleocapsid Protein

  • 2019-nCoV N Protein
  • 2019-nCoV Nucleocapsid Protein
  • COVID-19 N protein
  • COVID-19 nucleocapsid protein
  • Human coronavirus Nucleoprotein
  • Nucleocapsid protein
  • Nucleoprotein
  • SARS-CoV-2 Nucleocapsid protein
  • SARS-CoV-2 N protein
  • SARSCoV2 Nucleoprotein
  • Severe Acute Respiratory Syndrome Coronavirus 2 Nucleocapsid Protein

Background

Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). Seven coronaviruses had been found to cause human infection including SARS-CoV-2/2019-nCoV resulting in a potentially fatal atypical pneumonia, named COVID-19. SARS-CoV-2 has 4 major structural proteins including spike (S), envelope (E), membrane (M), and nucleocapsid (N), which share significant sequence homology with SARS-CoV. The most prominent protein in the culture supernatants infected with SARS virus is the 46 kDa nucleocapsid protein. SARS-CoV-2 nucleocapsid protein is critical for packaging the viral genome via protein oligomerization. Additionally, the SARS-CoV nucleocapsid protein has been implicated in other functions such as the modulation of host cellular processes including cell cycle deregulation, inhibition of IFN production, and induction of proinflammatory factors (e.g. COX-2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Publications for SARS-CoV-2 Nucleocapsid Recombinant Protein (NBP2-90975) (0)

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Other Available Formats

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