Respiratory Syncytial Virus Antibody (8B10cc) - BSA Free

Product Discontinued

Respiratory Syncytial Virus Antibody (8B10cc) - BSA Free Summary

• Immunogen: Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with purified RSV, strain Long.
• Specificity: Nucleoprotein (N) protein specific. NB120-10016 reacts only with mature virions with completely assembled nucleocapsids. It fails to reorganize the N-protein epitope of immature and destroyed virions, which indicates conformation dependence of the NB120-10016 binding site.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:2000
  • Lateral Flow Assay

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS (pH 7.4)
• Preservative: 0.09% Sodium Azide
• Purity: Protein A purified

Alternate Names for Respiratory Syncytial Virus Antibody (8B10cc) - BSA Free

• Fusion glycoprotein F0
• Fusion glycoprotein F1
• Fusion glycoprotein F2
• RS virus
• RSV

Background

Respiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. RSV infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. RSV is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, results in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.