Recombinant Human IgG1 Fc Protein, CF

Recombinant Human IgG1/Fc Protein (Catalog # 110-HG) has a molecular weight (MW) of 55.8 kDa as analyzed by SEC-MALS, suggesting that this protein is a dimer. MW may differ from predicted MW due to post-translational modifications (PTMs) present (i.e. Glycosylation).

• Reactivity: Hu
• Applications: Bioactivity
• Clonality: Polyclonal
• Host: Human
• Format: Carrier-Free
• Concentration: LYOPH

Recombinant Human IgG1 Fc Protein, CF Summary

• Additional Information: Analyzed by SEC-MALS
• Details of Functionality: Bioassay data are not available.
• Source: Mouse myeloma cell line, NS0-derived human IgG1 protein

  IEGRMD

  Human IgG 1 (Pro100-Lys330) Substitutions: Leu117Ala, Leu118Glu, Gly120Ala, Thr276Ala Accession # P01857.1

  N-terminus

  C-terminus

• Accession #: P01857.1
• N-terminal Sequence: Ile
• Structure / Form: Dimer
• Protein/Peptide Type: Recombinant Proteins
• Clonality: Polyclonal
• Host: Human
• Gene: IGHG1
• Purity: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
• Endotoxin Note: <0.10 EU per 1 μg of the protein by the LAL method.

Applications/Dilutions

• Dilutions:
  • Bioactivity
• Theoretical MW: 26.6 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• SDS-PAGE: 30-35 kDa, reducing conditions

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 3 months, -20 to -70 degreesC under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
• Reconstitution Instructions: It is recommended that sterile PBS containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of no less than 100 μg/mL.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Recombinant Human IgG1 Fc Protein, CF

• IgG1
• Igh-4
• RGD1359539
• VH7183

Background

R&D Systems offers a range of secondary antibodies and controls for flow cytometry, immunohistochemistry, and Western blotting. We provide species-specific secondary antibodies that are available with a variety of conjugated labels. Our NorthernLights fluorescent secondary antibodies are bright and resistant to photobleaching. We are currently offering secondary antibodies recognizing mouse, rat, goat, sheep, and rabbit IgG as well as chicken IgY. These reagents are available with three distinct excitation and emission maxima, making them ideal for multi-color fluorescence microscopy.

Publications for IgG1 (110-HG)(128)

Publications using 110-HG

• Cho, S;Servián-Morilla, E;Garrido, VN;Rodriguez-Gonzalez, B;Yuan, Y;Cano, R;Rambhiya, AA;Darabi, R;Haltiwanger, RS;Paradas, C;Jafar-Nejad, H; The glycosyltransferase POGLUT1 regulates muscle stem cell development and maintenance in mice bioRxiv : the preprint server for biology 2024-11-25 [PMID: 39651163] (Bioassay, Mouse)
• Alvarez, JA;Gas-Pascual, E;Malhi, S;Sánchez-Arcila, JC;Njume, FN;van der Wel, H;Zhao, Y;García-López, L;Ceron, G;Posada, J;Souza, SP;Yap, GS;West, CM;Jensen, KDC; The GPI sidechain of Toxoplasma gondii inhibits parasite pathogenesis mBio 2024-09-20 [PMID: 39302131] (Bioassay, T. gondii)
• Guo, S;Wang, Y;Duan, Q;Gu, W;Fu, Q;Ma, Z;Ruan, J; Activation of EphrinB2/EphB2 signaling in the spine cord alters glia-neuron interactions in mice with visceral hyperalgesia following maternal separation Frontiers in pharmacology 2024-09-03 [PMID: 39290870] (In vivo assay, Mouse)
• Liu, T;Wu, G;Gudd, CLC;Trovato, FM;Barbera, T;Liu, Y;Triantafyllou, E;McPhail, MJW;Thursz, MR;Khamri, W; Cis-interaction between CD52 and T cell receptor complex interferes with CD4+ T cell activation in acute decompensation of cirrhosis EBioMedicine 2024-09-13 [PMID: 39276679] (Bioassay, Human)
• Stewen, J;Kruse, K;Godoi-Filip, AT;Zenia, ;Jeong, HW;Adams, S;Berkenfeld, F;Stehling, M;Red-Horse, K;Adams, RH;Pitulescu, ME; Eph-ephrin signaling couples endothelial cell sorting and arterial specification Nature communications 2024-04-03 [PMID: 38570531] (Bioassay, Human)
• Rhymes, ER;Simkin, RL;Qu, J;Villarroel-Campos, D;Surana, S;Tong, Y;Shapiro, R;Burgess, RW;Yang, XL;Schiavo, G;Sleigh, JN; Boosting BDNF in muscle rescues impaired axonal transport in a mouse model of DI-CMTC peripheral neuropathy bioRxiv : the preprint server for biology 2024-03-11 [PMID: 38559020] (Immunoprecipitation, Mouse)
• Martins, C;Rasbach, E;Heppt, MV;Singh, P;Kulcsar, Z;Holzgruber, J;Chakraborty, A;Mucciarone, K;Kleffel, S;Brandenburg, A;Hoetzenecker, W;Rahbari, NN;DeCaprio, JA;Thakuria, M;Murphy, GF;Ramsey, MR;Posch, C;Barthel, SR;Schatton, T; Tumor cell-intrinsic PD-1 promotes Merkel cell carcinoma growth by activating downstream mTOR-mitochondrial ROS signaling Science advances 2024-01-19 [PMID: 38241371] (Bioassay, Human)
• Tsai, CH;Liu, E;Phan, A;Lu, KL;Mei, H; NBL1 Reduces Corneal Fibrosis and Scar Formation after Wounding Biomolecules 2023-10-24 [PMID: 38002252] (Bioassay, Human, Mouse)
• Erlichman, N;Meshel, T;Baram, T;Abu Raiya, A;Horvitz, T;Ben-Yaakov, H;Ben-Baruch, A; The Cell-Autonomous Pro-Metastatic Activities of PD-L1 in Breast Cancer Are Regulated by N-Linked Glycosylation-Dependent Activation of STAT3 and STAT1 Cells 2023-09-23 [PMID: 37830552] (Bioassay, Human)
• Mellergaard, M;Skovbakke, SL;Jepsen, SD;Panagiotopoulou, N;Hansen, ABR;Tian, W;Lund, A;Høgh, RI;Møller, SH;Guérillot, R;Hayes, AS;Erikstrup, LT;Andresen, L;Peleg, AY;Larsen, AR;Stinear, TP;Handberg, A;Erikstrup, C;Howden, BP;Goletz, S;Frees, D;Skov, S; Clinical Staphylococcus aureus inhibits human T-cell activity through interaction with the PD-1 receptor mBio 2023-10-05 [PMID: 37796131] (Flow Cytometry Control, Human)
• Lenza, MP;Egia-Mendikute, L;Antoñana-Vildosola, A;Soares, CO;Coelho, H;Corzana, F;Bosch, A;Manisha, P;Quintana, JI;Oyenarte, I;Unione, L;Moure, MJ;Azkargorta, M;Atxabal, U;Sobczak, K;Elortza, F;Sutherland, JD;Barrio, R;Marcelo, F;Jiménez-Barbero, J;Palazon, A;Ereño-Orbea, J; Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b Nature communications 2023-06-13 [PMID: 37311743] (Bioassay, Human)
• Li, X;Li, J;Zheng, Y;Lee, SJ;Zhou, J;Giobbie-Hurder, A;Butterfield, LH;Dranoff, G;Hodi, FS; Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Influence on Soluble and Membrane Bound ICOS in Combination with Immune Checkpoint Blockade Cancer immunology research 2023-06-01 [PMID: 37262321] (Neutralization Control, Human)
• Adel, SS;Clarke, VRJ;Evans-Strong, A;Maguire, J;Paradis, S; Semaphorin 4D induced inhibitory synaptogenesis decreases epileptiform activity and alters progression to Status Epilepticus in mice Epilepsy research 2023-04-27 [PMID: 37163910] (Bioassay, Mouse)
• CA Hokanson, E Zacco, G Cappuccill, T Odineca, R Crea AXL-Receptor Targeted 14FN3 Based Single Domain Proteins (Pronectins�) from 3 Synthetic Human Libraries as Components for Exploring Novel Bispecific Constructs against Solid Tumors Biomedicines, 2022-12-08;10(12):. 2022-12-08 [PMID: 36551940] (Bioassay, Mouse)
• S Tian, X Xiong, J Zeng, S Wang, BJ Tremblay, P Chen, B Chen, M Liu, P Chen, K Sheng, D Zeve, W Qi, DT Breault, C Rodríguez, R Gerhard, R Jin, AC Doxey, M Dong Identification of TFPI as a receptor reveals recombination-driven receptor switching in Clostridioides difficile toxin B variants Nature Communications, 2022-11-09;13(1):6786. 2022-11-09 [PMID: 36351897] (Reference Standard, Human)
• K Szabó, I Jámbor, K Pázmándi, N Nagy, G Papp, T Tarr Altered Circulating Follicular T Helper Cell Subsets and Follicular T Regulatory Cells Are Indicators of a Derailed B Cell Response in Lupus, Which Could Be Modified by Targeting IL-21R International Journal of Molecular Sciences, 2022-10-13;23(20):. 2022-10-13 [PMID: 36293075] (Cell Culture, Human)
• Y Murayama, Y Kasahara, N Kubo, C Shin, M Imamura, N Oike, T Ariizumi, A Saitoh, M Baba, T Miyazaki, Y Suzuki, Y Ling, S Okuda, K Mihara, A Ogose, H Kawashima, C Imai NKp44-based chimeric antigen receptor effectively redirects primary T cells against synovial sarcoma Translational Oncology, 2022-08-20;25(0):101521. 2022-08-20 [PMID: 35998437] (Flow Cytometry, Human)
• C Martins, M Silva, E Rasbach, P Singh, Y Itoh, JB Williams, E Statham, A Meurer, DV Martinez, A Brandenbur, MV Heppt, SR Barthel, T Schatton Distinct antibody clones detect PD-1 checkpoint expression and block PD-L1 interactions on live murine melanoma cells Scientific Reports, 2022-07-21;12(1):12491. 2022-07-21 [PMID: 35864188] (Bioassay, Mouse)
• N Gioelli, LJ Neilson, N Wei, G Villari, W Chen, B Kuhle, M Ehling, F Maione, S Willox, S Brundu, D Avanzato, G Koulouras, M Mazzone, E Giraudo, XL Yang, D Valdembri, S Zanivan, G Serini Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability Nature Communications, 2022-07-20;13(1):4188. 2022-07-20 [PMID: 35858913] (Bioassay, Human)
• SL Banerjee, F Lessard, FJM Chartier, K Jacquet, AI Osornio-He, V Teyssier, K Ghani, N Lavoie, JN Lavoie, M Caruso, P Laprise, S Elowe, JP Lambert, N Bisson EPH receptor tyrosine kinases phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks Cell Reports, 2022-07-05;40(1):111031. 2022-07-05 [PMID: 35793621] (Bioassay, Human)
• NR Hansmeier, IS Büschlen, RY Behncke, S Ulferts, R Bisoendial, R Hägerling 3D Visualization of Human Blood Vascular Networks Using Single-Domain Antibodies Directed against Endothelial Cell-Selective Adhesion Molecule (ESAM) International Journal of Molecular Sciences, 2022-04-15;23(8):. 2022-04-15 [PMID: 35457187] (Bioassay, N/A)
• JH Cha, LC Chan, YN Wang, YY Chu, CH Wang, HH Lee, W Xia, WC Shyu, SP Liu, J Yao, CW Chang, FR Cheng, J Liu, SO Lim, JL Hsu, WH Yang, GN Hortobagyi, C Lin, L Yang, D Yu, LB Jeng, MC Hung Ephrin receptor A10 monoclonal antibodies and the derived chimeric antigen receptor T cells exert an antitumor response in mouse models of triple-negative breast cancer The Journal of Biological Chemistry, 2022-03-10;0(0):101817. 2022-03-10 [PMID: 35278434] (ELISA Capture, N/A)
• P Xiao, J Gu, W Xu, X Niu, J Zhang, J Li, Y Chen, Z Pei, J Zeng, S Xing RTN4/Nogo-A-S1PR2 negatively regulates angiogenesis and secondary neural repair through enhancing vascular autophagy in the thalamus after cerebral cortical infarction Autophagy, 2022-03-09;0(0):1-20. 2022-03-09 [PMID: 35263212] (In Vivo, Rat)
• N Erlichman, T Baram, T Meshel, D Morein, B Da'adoosh, A Ben-Baruch Tumor Cell-Autonomous Pro-Metastatic Activities of PD-L1 in Human Breast Cancer Are Mediated by PD-L1-S283 and Chemokine Axes Cancers, 2022-02-18;14(4):. 2022-02-18 [PMID: 35205789] (Bioassay, Human)
• M Kamiya, F Mizoguchi, K Kawahata, D Wang, M Nishibori, J Day, C Louis, IP Wicks, H Kohsaka, S Yasuda Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies Nature Communications, 2022-01-10;13(1):166. 2022-01-10 [PMID: 35013338] (Bioassay, Mouse)
• KL Clar, LM Weber, BJ Schmied, JS Heitmann, M Marconato, C Tandler, P Schneider, HR Salih Receptor Activator of NF-kappaB (RANK) Confers Resistance to Chemotherapy in AML and Associates with Dismal Disease Course Cancers, 2021-12-04;13(23):. 2021-12-04 [PMID: 34885231] (Bioassay, Human)
• CC Huang, TT Tseng, SC Liu, YY Lin, YY Law, SL Hu, SW Wang, CH Tsai, CH Tang S1P Increases VEGF Production in Osteoblasts and Facilitates Endothelial Progenitor Cell Angiogenesis by Inhibiting miR-16-5p Expression via the c-Src/FAK Signaling Pathway in Rheumatoid Arthritis Cells, 2021-08-23;10(8):. 2021-08-23 [PMID: 34440937] (Human)
• PM Horvath, NL Chanaday, B Alten, ET Kavalali, LM Monteggia A subthreshold synaptic mechanism regulating BDNF expression and resting synaptic strength Cell Reports, 2021-08-03;36(5):109467. 2021-08-03 [PMID: 34348149] (Reference Standard, Rat)
• CM Bryan, GJ Rocklin, MJ Bick, A Ford, S Majri-Morr, AV Kroll, CJ Miller, L Carter, I Goreshnik, A Kang, F DiMaio, KV Tarbell, D Baker Computational design of a synthetic PD-1 agonist Proceedings of the National Academy of Sciences of the United States of America, 2021-07-20;118(29):. 2021-07-20 [PMID: 34272285] (Bioassay, Mouse)
• M Ogishi, R Yang, C Aytekin, D Langlais, M Bourgey, T Khan, FA Ali, M Rahman, OM Delmonte, M Chrabieh, P Zhang, C Gruber, SJ Pelham, AN Spaan, J Rosain, WT Lei, S Drutman, MD Hellmann, MK Callahan, M Adamow, P Wong, JD Wolchok, G Rao, CS Ma, Y Nakajima, T Yaguchi, K Chamoto, SC Williams, JF Emile, F Rozenberg, MS Glickman, F Rapaport, G Kerner, G Allington, I Tezcan, D Cagdas, FO Hosnut, F Dogu, A Ikinciogul, VK Rao, L Kainulaine, V Béziat, J Bustamante, S Vilarinho, RP Lifton, B Boisson, L Abel, D Bogunovic, N Marr, LD Notarangel, SG Tangye, T Honjo, P Gros, S Boisson-Du, JL Casanova Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child Nature Medicine, 2021-06-28;0(0):. 2021-06-28 [PMID: 34183838] (Bioassay, Human)
• M Passariell, C Gentile, V Ferrucci, E Sasso, C Vetrei, G Fusco, M Viscardi, S Brandi, P Cerino, N Zambrano, M Zollo, C De Lorenzo Novel human neutralizing mAbs specific for Spike-RBD of SARS-CoV-2 Scientific Reports, 2021-05-26;11(1):11046. 2021-05-26 [PMID: 34040046] (Affinity Purification, Human)
• P Shafiei-Ja, DG Helou, BP Hurrell, E Howard, C Quach, JD Painter, L Galle-Treg, M Li, YE Loh, O Akbari CD200-CD200R immune checkpoint engagement regulates ILC2 effector function and ameliorates lung inflammation in asthma Nature Communications, 2021-05-05;12(1):2526. 2021-05-05 [PMID: 33953190] (Bioassay, In Vivo, Human, Mouse)
• J Jukonen, L Moyano-Gal, K Höpfner, EA Pietilä, L Lehtinen, K Huhtinen, E Gucciardo, J Hynninen, S Hietanen, S Grénman, PM Ojala, O Carpén, K Lehti Aggressive and recurrent ovarian cancers upregulate ephrinA5, a non-canonical effector of EphA2 signaling duality Scientific Reports, 2021-04-23;11(1):8856. 2021-04-23 [PMID: 33893375] (Bioassay, Human)
• Y Shang, X Zhang, L Lu, K Jiang, M Krohn, S Matschos, CS Mullins, B Vollmar, D Zechner, P Gong, M Linnebache Pharmaceutical immunoglobulin G impairs anti-carcinoma activity of oxaliplatin in colon cancer cells British Journal of Cancer, 2021-02-09;0(0):. 2021-02-09 [PMID: 33558709] (Bioassay, Human)
• S C Khouili, ECL Cook, E Hernández-, M Martínez-L, R Conde-Garr, S Iborra SHP-1 Regulates Antigen Cross-Presentation and Is Exploited by Leishmania to Evade Immunity Cell Rep, 2020-12-01;33(9):108468. 2020-12-01 [PMID: 33264612] (Cell Culture, Mouse)
• AN Gonçalves, J Correia-Pi, C Nogueira-S ROBO2 signaling in lung development regulates SOX2/SOX9 balance, branching morphogenesis and is dysregulated in nitrofen-induced congenital diaphragmatic hernia Respir Res, 2020-11-18;21(1):302. 2020-11-18 [PMID: 33208157] (Cell Culture, Rat)
• Tun Wang, Jia Liu, Haiyang Liu, Shin-Rong Lee, Luis Gonzalez, Jolanta Gorecka et al. Activation of EphrinB2 Signaling Promotes Adaptive Venous Remodeling in Murine Arteriovenous Fistulae Journal of Surgical Research 2021-06-01 [PMID: 33039109] (Bioassay, In vivo assay, Mouse)
• V Ponath, M Frech, M Bittermann, R Al Khayer, A Neubauer, C Brendel, E Pogge von The Oncoprotein SKI Acts as A Suppressor of NK Cell-Mediated Immunosurveillance in PDAC Cancers (Basel), 2020-10-03;12(10):. 2020-10-03 [PMID: 33023028] (Bioassay, Human)
• MC Cavé, S Maillard, K Hildenbran, C Mamelonet, MJ Feige, O Devergne Glycosaminoglycans bind human IL-27 and regulate its activity Eur. J. Immunol., 2020-07-02;0(0):. 2020-07-02 [PMID: 32483835] (Bioassay, Human)
• C Volz, S Breid, C Selenz, A Zaplatina, K Golfmann, L Meder, F Dietlein, S Borchmann, S Chatterjee, M Siobal, J Schöttle, A Florin, M Koker, M Nill, L Ozreti?, N Uhlenbrock, S Smith, R Büttner, H Miao, B Wang, HC Reinhardt, D Rauh, M Hallek, A Acker-Palm, LC Heukamp, RT Ullrich Inhibition of Tumor VEGFR2 Induces Serine 897 EphA2-Dependent Tumor Cell Invasion and Metastasis in NSCLC Cell Rep, 2020-04-28;31(4):107568. 2020-04-28 [PMID: 32348765] (Bioassay, Human)
• J Huetter, U Gritzan, I Gutcher, WD Doecke, MV Luetke-Eve, S Golfier, HG Roider, AL Frisk, J Hunter, A Pow, A Drake, Z Levine, O Levy, M Azulay, I Barbiro, G Cojocaru, I Vaknin, B Kreft, L Roese Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) Cancer Immunol Res, 2020-04-20;8(7):895-911. 2020-04-20 [PMID: 32312711] (Bioassay, Human)
• DY Yuh, T Maekawa, X Li, T Kajikawa, K Bdeir, T Chavakis, G Hajishenga The secreted protein DEL-1 activates a beta3 integrin-FAK-ERK1/2-RUNX2 pathway and promotes osteogenic differentiation and bone regeneration J. Biol. Chem., 2020-04-12;295(21):7261-7273. 2020-04-12 [PMID: 32280065] (Bioassay, In Vivo, Mouse, Transgenic Mouse)
• VR Graziano, FC Walker, EA Kennedy, J Wei, K Ettayebi, MS Strine, RB Filler, E Hassan, LL Hsieh, AS Kim, AO Kolawole, CE Wobus, LC Lindesmith, RS Baric, MK Estes, RC Orchard, MT Baldridge, CB Wilen CD300lf is the primary physiologic receptor of murine norovirus but not human norovirus PLoS Pathog., 2020-04-06;16(4):e1008242. 2020-04-06 [PMID: 32251490] (Cell Culture, Human)
• G Luxán, J Stewen, N Díaz, K Kato, SK Maney, A Aravamudha, F Berkenfeld, N Nagelmann, HC Drexler, D Zeuschner, C Faber, H Schillers, S Hermann, J Wiseman, JM Vaquerizas, ME Pitulescu, RH Adams Endothelial EphB4 maintains vascular integrity and transport function in adult heart Elife, 2019-11-29;8(0):. 2019-11-29 [PMID: 31782728] (Cell Culture, Human)
• M Yamada, Y Fujita, Y Hayano, H Hayakawa, K Baba, H Mochizuki, T Yamashita Increased expression of fibronectin leucine-rich transmembrane protein 3 in the dorsal root ganglion induces neuropathic pain in rats J. Neurosci., 2019-07-25;0(0):. 2019-07-25 [PMID: 31346030] (ELISA Capture, Human)
• J Casulli, ME Fife, SA Houston, S Rossi, J Dow, ED Williamson, GC Clark, T Hussell, RV D'Elia, MA Travis CD200R deletion promotes a neutrophil niche for Francisella tularensis and increases infectious burden and mortality Nat Commun, 2019-05-09;10(1):2121. 2019-05-09 [PMID: 31073183] (In Vivo, Mouse)
• O Theodoly, N Garcia-Sey, F Bedu, X Luo, S Gabriele, T Mignot, J Giermanska, JP Chapel, M Métivier, MP Valignat Live nanoscopic to mesoscopic topography reconstruction with an optical microscope for chemical and biological samples PLoS ONE, 2018-12-12;13(12):e0207881. 2018-12-12 [PMID: 30540777] (Bioassay, Human)
• J Yoon, YS Hwang, M Lee, J Sun, HJ Cho, L Knapik, IO Daar TBC1d24-ephrinB2 interaction regulates contact inhibition of locomotion in neural crest cell migration Nat Commun, 2018-08-28;9(1):3491. 2018-08-28 [PMID: 30154457] (Bioassay, Xenopus)
• H Tsukamoto, K Fujieda, A Miyashita, S Fukushima, T Ikeda, Y Kubo, S Senju, H Ihn, Y Nishimura, H Oshiumi Combined blockade of IL-6 and PD-1/PD-L1 signaling abrogates mutual regulation of their immunosuppressive effects in the tumor microenvironment Cancer Res., 2018-07-02;0(0):. 2018-07-02 [PMID: 29967259] (Bioassay, Mouse)
• KK Rasmussen, MH Falkesgaar, M Winther, NK Roed, CL Quistgaard, MN Teisen, SM Edslev, DL Petersen, A Aljubouri, C Christense, PW Thulstrup, L Lo Leggio, K Teilum, PS Walmod NCAM2 Fibronectin type-III domains form a rigid structure that binds and activates the Fibroblast Growth Factor Receptor Sci Rep, 2018-06-12;8(1):8957. 2018-06-12 [PMID: 29895898] (Bioassay)
• AT Kurdi, SV Glavey, NA Bezman, A Jhatakia, JL Guerriero, S Manier, M Moschetta, Y Mishima, A Roccaro, A Detappe, CJ Liu, A Sacco, D Huynh, YT Tai, MD Robbins, J Azzi, IM Ghobrial Antibody dependent cellular phagocytosis by macrophages is a novel mechanism of action of elotuzumab Mol. Cancer Ther., 2018-04-13;0(0):. 2018-04-13 [PMID: 29654064] (In Vivo, Mouse)
• Y Zhao, X Wu, X Li, LL Jiang, X Gui, Y Liu, Y Sun, B Zhu, JC Piña-Cresp, M Zhang, N Zhang, X Chen, G Bu, Z An, TY Huang, H Xu TREM2 Is a Receptor for ?-Amyloid that Mediates Microglial Function Neuron, 2018-03-07;97(5):1023-1031.e7. 2018-03-07 [PMID: 29518356] (Bioassay, Immunoprecipitation, Human)
• NA Warren, G Voloudakis, Y Yoon, NK Robakis, A Georgakopo The product of the ?-secretase processing of ephrinB2 regulates VE-cadherin complexes and angiogenesis Cell. Mol. Life Sci., 2018-02-10;0(0):. 2018-02-10 [PMID: 29428965] (Bioassay, Bovine)
• A DuSablon, J Parks, K Whitehurst, H Estes, R Chase, E Vlahos, U Sharma, D Wert, J Virag EphrinA1-Fc attenuates myocardial ischemia/reperfusion injury in mice PLoS ONE, 2017-12-13;12(12):e0189307. 2017-12-13 [PMID: 29236774] (In Vivo, Mouse)
• I Mitroulis, LS Chen, RP Singh, I Kourtzelis, M Economopou, T Kajikawa, M Troullinak, A Ziogas, K Ruppova, K Hosur, T Maekawa, B Wang, P Subramania, T Tonn, P Verginis, M von Bonin, M Wobus, M Bornhäuser, T Grinenko, M Di Scala, A Hidalgo, B Wielockx, G Hajishenga, T Chavakis Secreted protein Del-1 regulates myelopoiesis in the hematopoietic stem cell niche J. Clin. Invest., 2017-08-28;0(0):. 2017-08-28 [PMID: 28846069] (Bioassay, Mouse)
• L Yang, M Hansen Fal, PW Thulstrup, PS Walmod, L Lo Leggio, K Krighaar R Expression, refolding and spectroscopic characterization of fibronectin type III (FnIII)-homology domains derived from human fibronectin leucine rich transmembrane protein (FLRT)-1, -2, and -3 PeerJ, 2017-07-07;5(0):e3550. 2017-07-07 [PMID: 28698826] (Bioassay, Human)
• RR Nair, S Patil, A Tiron, T Kanhema, D Panja, L Schiro, K Parobczak, G Wilczynski, CR Bramham Dynamic Arc SUMOylation and Selective Interaction with F-Actin-Binding Protein Drebrin A in LTP Consolidation In Vivo Front Synaptic Neurosci, 2017-05-10;9(0):8. 2017-05-10 [PMID: 28553222] (In Vivo, Rat)
• S Nakachi, S Sumitomo, Y Tsuchida, H Tsuchiya, M Kono, R Kato, K Sakurai, N Hanata, Y Nagafuchi, S Tateishi, H Kanda, T Okamura, K Yamamoto, K Fujio Interleukin-10-producing LAG3(+) regulatory T cells are associated with disease activity and abatacept treatment in rheumatoid arthritis Arthritis Res. Ther., 2017-05-16;19(1):97. 2017-05-16 [PMID: 28511719] (Bioassay, Human)
• S Gehler, FV Compere, AM Miller Semaphorin 3A Increases FAK Phosphorylation at Focal Adhesions to Modulate MDA-MB-231 Cell Migration and Spreading on Different Substratum Concentrations Int J Breast Cancer, 2017-01-15;2017(0):9619734. 2017-01-15 [PMID: 28182100] (Bioassay, Human)
• Wei Wei ICAM-5/Telencephalin Is a Functional Entry Receptor for Enterovirus D68 Cell Host Microbe, 2016-10-27;20(5):631-641. 2016-10-27 [PMID: 27923705] (Bioassay)
• Tissue factor is induced by interleukin-33 in human endothelial cells: a new link between coagulation and inflammation Sci Rep, 2016-05-04;6(0):25171. 2016-05-04 [PMID: 27142573] (Bioassay, Human)
• Roth J, Kohler D, Schneider M, Granja T, Rosenberger P Semaphorin 7A Aggravates Pulmonary Inflammation during Lung Injury. PLoS ONE, 2016-01-11;11(1):e0146930. 2016-01-11 [PMID: 26752048] (Control, Human)
• Zhang P, Feng S, Liu G, Wang H, Zhu H, Ren Q, Bai H, Fu C, Dong C Mutant B-Raf(V600E) Promotes Melanoma Paracellular Transmigration by Inducing Thrombin-mediated Endothelial Junction Breakdown. J Biol Chem, 2015-10-26;291(5):2087-106. 2015-10-26 [PMID: 26504080] (Bioassay, Human)
• Xing R, Yang L, Jin Y, Sun L, Li C, Li Z, Zhao J, Liu X Interleukin-21 Induces Proliferation and Proinflammatory Cytokine Profile of Fibroblast-like Synoviocytes of Patients with Rheumatoid Arthritis. Scand J Immunol, 2016-01-01;83(1):64-71. 2016-01-01 [PMID: 26482544] (Bioassay, Human)
• Liu T, Kanaoka Y, Barrett N, Feng C, Garofalo D, Lai J, Buchheit K, Bhattacharya N, Laidlaw T, Katz H, Boyce J Aspirin-Exacerbated Respiratory Disease Involves a Cysteinyl Leukotriene-Driven IL-33-Mediated Mast Cell Activation Pathway. J Immunol, 2015-09-04;195(8):3537-45. 2015-09-04 [PMID: 26342029] (In Vivo, Mouse)
• Zou Y, Bao J, Pan X, Lu Y, Liao S, Wang X, Wang G, Lin D NKP30-B7-H6 Interaction Aggravates Hepatocyte Damage through Up-Regulation of Interleukin-32 Expression in Hepatitis B Virus-Related Acute-On-Chronic Liver Failure. PLoS ONE, 2015-08-04;10(8):e0134568. 2015-08-04 [PMID: 26241657] (Control, Human)
• Park I, Mundy-Bosse B, Whitman S, Zhang X, Warner S, Bearss D, Blum W, Marcucci G, Caligiuri M Receptor tyrosine kinase Axl is required for resistance of leukemic cells to FLT3-targeted therapy in acute myeloid leukemia. Leukemia, 2015-06-19;29(12):2382-9. 2015-06-19 [PMID: 26172401] (Bioassay, Human)
• Veit T, Chies J, Switala M, Wagner B, Horn P, Busatto M, Brenol C, Tavares Brenol J, Machado Xavier R, Rebmann V The paradox of high availability and low recognition of soluble HLA-G by LILRB1 receptor in rheumatoid arthritis patients. PLoS ONE, 2015-04-08;10(4):e0123838. 2015-04-08 [PMID: 25853899] (Bioassay, Human)
• Salvucci O, Ohnuki H, Maric D, Hou X, Li X, Yoon S, Segarra M, Eberhart C, Acker-Palmer A, Tosato G EphrinB2 controls vessel pruning through STAT1-JNK3 signalling. Nat Commun, 2015-03-26;6(0):6576. 2015-03-26 [PMID: 25807892] (Bioassay, Human)
• Panneerselvam J, Jin J, Shanker M, Lauderdale J, Bates J, Wang Q, Zhao Y, Archibald S, Hubin T, Ramesh R IL-24 inhibits lung cancer cell migration and invasion by disrupting the SDF-1/CXCR4 signaling axis. PLoS ONE, 2015-03-16;10(3):e0122439. 2015-03-16 [PMID: 25775124] (Human)
• Ahn , Seong Be, Chan , Charles, Dent , Owen F, Mohamedali , Abidali, Kwun , Sun Youn, Clarke , Candice, Fletcher , Julie, Chapuis , Pierre H, Nice , Edouard, Baker , Mark S Epithelial and stromal cell urokinase plasminogen activator receptor expression differentially correlates with survival in rectal cancer stages B and C patients. PLoS ONE, 2015-02-18;10(2):e0117786. 2015-02-18 [PMID: 25692297] (IHC-P, Human)
• Herova M, Schmid M, Gemperle C, Hersberger M ChemR23, the receptor for chemerin and resolvin E1, is expressed and functional on M1 but not on M2 macrophages. J Immunol, 2015-01-30;194(5):2330-7. 2015-01-30 [PMID: 25637017] (Isotype Control, Human)
• Zhu G, Liu Y, Wang Y, Bi X, Baudry M Different patterns of electrical activity lead to long-term potentiation by activating different intracellular pathways. J Neurosci, 2015-01-14;35(2):621-33. 2015-01-14 [PMID: 25589756] (Control, Mouse)
• Morrison A, Yarovinsky T, Young B, Moraes F, Ross T, Ceneri N, Zhang J, Zhuang Z, Sinusas A, Pardi R, Schwartz M, Simons M, Bender J Chemokine-coupled beta2 integrin-induced macrophage Rac2-Myosin IIA interaction regulates VEGF-A mRNA stability and arteriogenesis. J Exp Med, 2014-09-01;211(10):1957-68. 2014-09-01 [PMID: 25180062] (Bioassay, Human)
• Ono , Katsuhik, Clavairoly , Adrien, Nomura , Tadashi, Gotoh , Hitoshi, Uno , Aoi, Armant , Olivier, Takebayashi , Hirohide, Zhang , Qi, Shimamura , Kenji, Itohara , Shigeyos, Parras , Carlos M, Ikenaka , Kazuhiro Development of the prethalamus is crucial for thalamocortical projection formation and is regulated by Olig2. Development, 2014-05-01;141(10):2075-84. 2014-05-01 [PMID: 24803655] (Control, Mouse)
• Robinet P, Baychelier F, Fontaine T, Picard C, Debre P, Vieillard V, Latge J, Elbim C A polysaccharide virulence factor of a human fungal pathogen induces neutrophil apoptosis via NK cells. J Immunol, 2014-04-30;192(11):5332-42. 2014-04-30 [PMID: 24790151] (Isotype Control, Human)
• Rittase , W Bradle, Dong , Yu, Barksdale , DaRel, Galdzicki , Zygmunt, Bausch , Suzanne Dynorphin up-regulation in the dentate granule cell mossy fiber pathway following chronic inhibition of GluN2B-containing NMDAR is associated with increased CREB (Ser 133) phosphorylation, but is independent of BDNF/TrkB signaling pathways. Mol Cell Neurosci, 2014-04-23;60(0):63-71. 2014-04-23 [PMID: 24769103] (Control, Rat)
• Lines J, Pantazi E, Mak J, Sempere L, Wang L, O'Connell S, Ceeraz S, Suriawinata A, Yan S, Ernstoff M, Noelle R VISTA is an immune checkpoint molecule for human T cells. Cancer Res, 2014-04-01;74(7):1924-32. 2014-04-01 [PMID: 24691993] (Bioassay, Human)
• Wilhelmsen K, Khakpour S, Tran A, Sheehan K, Schumacher M, Xu F, Hellman J The endocannabinoid/endovanilloid N-arachidonoyl dopamine (NADA) and synthetic cannabinoid WIN55,212-2 abate the inflammatory activation of human endothelial cells. J Biol Chem, 2014-03-18;289(19):13079-100. 2014-03-18 [PMID: 24644287] (Human)
• Weinandy , Stefan, Babczyk , Patrick, Dreier , Agnieszk, Unger , Ronald E, Flanagan , Thomas C, Kirkpatrick , C James, Zenke , Martin, Klee , Doris, Jockenhoevel , Stefan Ovine carotid artery-derived cells as an optimized supportive cell layer in 2-D capillary network assays. PLoS ONE, 2014-03-12;9(3):e91664. 2014-03-12 [PMID: 24621607] (Flow Cytometry Control, Human)
• Ramkhelawon B, Hennessy E, Menager M, Ray T, Sheedy F, Hutchison S, Wanschel A, Oldebeken S, Geoffrion M, Spiro W, Miller G, McPherson R, Rayner K, Moore K Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity. Nat Med, 2014-03-02;20(4):377-84. 2014-03-02 [PMID: 24584118] (Bioassay, Mouse)
• Evans H, Roostalu U, Walter G, Gullick N, Frederiksen K, Roberts C, Sumner J, Baeten D, Gerwien J, Cope A, Geissmann F, Kirkham B, Taams L TNF-alpha blockade induces IL-10 expression in human CD4+ T cells. Nat Commun, 2014-01-01;5(0):3199. 2014-01-01 [PMID: 24492460] (Bioassay, Human)
• Li M, Rao C, Pei D, Wang L, Li Y, Gao K, Wang M, Wang J Novaferon, a novel recombinant protein produced by DNA-shuffling of IFN-alpha, shows antitumor effect in vitro and in vivo. Cancer Cell Int, 2014-01-27;14(1):8. 2014-01-27 [PMID: 24467885] (Surface Plasmon Resonance)
• Hasebe N, Fujita Y, Ueno M, Yoshimura K, Fujino Y, Yamashita T Soluble beta-amyloid Precursor Protein Alpha binds to p75 neurotrophin receptor to promote neurite outgrowth. PLoS ONE, 2013-12-16;8(12):e82321. 2013-12-16 [PMID: 24358169] (Functional ELISA, Human)
• Di Pardo A, Alberti S, Maglione V, Amico E, Cortes E, Elifani F, Battaglia G, Busceti C, Nicoletti F, Vonsattel J, Squitieri F Changes of peripheral TGF-beta1 depend on monocytes-derived macrophages in Huntington disease. Mol Brain, 2013-12-13;6(0):55. 2013-12-13 [PMID: 24330808] (Flow Cytometry Control, Human)
• Banks , Jessica, Herman , Christin, Bailey , Ryan C Bromelain decreases neutrophil interactions with P-selectin, but not E-selectin, in vitro by proteolytic cleavage of P-selectin glycoprotein ligand-1. PLoS ONE, 2013-11-11;8(11):e78988. 2013-11-11 [PMID: 24244398] (Bioassay)
• Szepietowska , Barbara, Horvath , Tamas L, Sherwin , Robert S Role of synaptic plasticity and EphA5-ephrinA5 interaction within the ventromedial hypothalamus in response to recurrent hypoglycemia. Diabetes, 2013-11-12;63(3):1140-7. 2013-11-12 [PMID: 24222347] (In Vivo, Rat)
• Ibusuki A, Kawai K, Yoshida S, Uchida Y, Nitahara-Takeuchi A, Kuroki K, Kajikawa M, Ose T, Maenaka K, Kasahara M, Kanekura T NKG2D triggers cytotoxicity in murine epidermal gammadelta T cells via PI3K-dependent, Syk/ZAP70-independent signaling pathway. J Invest Dermatol, 2013-08-20;134(2):396-404. 2013-08-20 [PMID: 23962808] (Bioassay, Mouse)
• Dessarthe B, Thedrez A, Latouche J, Cabillic F, Drouet A, Daniel P, de La Pintiere C, Catros V, Toutirais O CRTAM receptor engagement by Necl-2 on tumor cells triggers cell death of activated Vgamma9Vdelta2 T cells. J Immunol, 2013-03-25;190(9):4868-76. 2013-03-25 [PMID: 23530148] (Bioassay, Human)
• Mazerolles F, Picard C, Kracker S, Fischer A, Durandy A Blood CD4+CD45RO+CXCR5+ T cells are decreased but partially functional in signal transducer and activator of transcription 3 deficiency. J Allergy Clin Immunol, 2013-02-10;131(4):1146-56, 1156. 2013-02-10 [PMID: 23403044] (Bioassay, Human)
• Szepietowska B, Zhu W, Czyzyk J, Eid T, Sherwin R EphA5-EphrinA5 interactions within the ventromedial hypothalamus influence counterregulatory hormone release and local glutamine/glutamate balance during hypoglycemia. Diabetes, 2012-12-28;62(4):1282-8. 2012-12-28 [PMID: 23274893] (Rat)
• Peppa , Dimitra, Gill , Upkar S, Reynolds , Gary, Easom , Nicholas, Pallett , Laura J, Schurich , Anna, Micco , Lorenzo, Nebbia , Gaia, Singh , Harsimra, Adams , David H, Kennedy , Patrick, Maini , Mala K Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell-mediated deletion. J Exp Med, 2012-12-17;210(1):99-114. 2012-12-17 [PMID: 23254287] (Control, Human)
• Interleukin-33 overexpression is associated with gamma-glutamyl transferase in biliary atresia. Cytokine, 2012-11-22;61(2):433-7. 2012-11-22 [PMID: 23178147] (Bioassay, Human)
• Segarra , Marta, Ohnuki , Hidetaka, Maric , Dragan, Salvucci , Ombretta, Hou , Xu, Kumar , Anil, Li , Xuri, Tosato , Giovanna Semaphorin 6A regulates angiogenesis by modulating VEGF signaling. Blood, 2012-09-24;120(19):4104-15. 2012-09-24 [PMID: 23007403] (Bioassay, Human)
• Sundlisaeter E, Edelmann R, Hol J, Sponheim J, Kuchler A, Weiss M, Udalova I, Midwood K, Kasprzycka M, Haraldsen G The alarmin IL-33 is a notch target in quiescent endothelial cells. Am J Pathol, 2012-07-16;181(3):1099-111. 2012-07-16 [PMID: 22809957] (Control, Human)
• Benito-Miguel M, Garcia-Carmona Y, Balsa A, Bautista-Caro MB, Arroyo-Villa I, Cobo-Ibanez T, Bonilla-Hernan MG, De Ayala CP, Sanchez-Mateos P, Martin-Mola E, Miranda-Carus ME IL-15 Expression on RA Synovial Fibroblasts Promotes B Cell Survival. PLoS ONE, 2012-07-09;7(7):e40620. 2012-07-09 [PMID: 22792388] (Control, Human)
• Onal M, Xiong J, Chen X, Thostenson J, Almeida M, Manolagas S Receptor activator of nuclear factor kappaB ligand (RANKL) protein expression by B lymphocytes contributes to ovariectomy-induced bone loss. Oncogene, 2012-07-10;287(35):29851-60. 2012-07-10 [PMID: 22782898] (Control, Mouse)
• DcR3 binds to ovarian cancer via heparan sulfate proteoglycans and modulates tumor cells response to platinum with corresponding alteration in the expression of BRCA1. BMC Cancer, 2012-05-14;12(0):176. 2012-05-14 [PMID: 22583667] (Control, Human)
• de Freitas A, Banerjee S, Xie N Identification of TLT2 as an engulfment receptor for apoptotic cells. J. Immunol., 2012-05-09;188(12):6381-8. 2012-05-09 [PMID: 22573805] (In Vivo, Mouse)
• Dewannieux M, Vernochet C, Ribet D, Bartosch B, Cosset FL, Heidmann T The mouse IAPE endogenous retrovirus can infect cells through any of the five GPI-anchored Ephrin A proteins. PLoS Pathog., 2011-10-20;7(10):e1002309. 2011-10-20 [PMID: 22028653] (Control, Mouse)
• Ricano-Cornejo I, Altick AL, Garcia-Pena CM, Nural HF, Echevarria D, Miquelajauregui A, Mastick GS, Varela-Echavarria A Slit-Robo signals regulate pioneer axon pathfinding of the tract of the postoptic commissure in the mammalian forebrain. J. Neurosci. Res., 2011-06-17;89(10):1531-41. 2011-06-17 [PMID: 21688288] (Mouse)
• Brantley-Sieders DM, Dunaway CM, Rao M Angiocrine factors modulate tumor proliferation and motility through EphA2 repression of Slit2 tumor suppressor function in endothelium. Cancer Res., 2010-12-08;71(3):976-87. 2010-12-08 [PMID: 21148069] (Control, Mouse)
• Nomura T, Goritz C, Catchpole T, Henkemeyer M, Frisen J EphB signaling controls lineage plasticity of adult neural stem cell niche cells. Cell Stem Cell, 2010-12-03;7(6):730-43. 2010-12-03 [PMID: 21112567] (Control, Mouse)
• Uniewicz KA, Cross MJ, Fernig DG Exogenous recombinant dimeric neuropilin-1 is sufficient to drive angiogenesis. J. Biol. Chem., 2010-10-18;286(1):12-23. 2010-10-18 [PMID: 20956519] (Control, Human)
• Sawamiphak S, Seidel S, Essmann CL, Wilkinson GA, Pitulescu ME, Acker T, Acker-Palmer A Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis. Nature, 2010-05-05;465(7297):487-91. 2010-05-05 [PMID: 20445540] (Control, Mouse)
• Lamprecht B, Walter K, Kreher S, Kumar R, Hummel M, Lenze D, Kochert K, Bouhlel MA, Richter J, Soler E, Stadhouders R, Johrens K, Wurster KD, Callen DF, Harte MF, Giefing M, Barlow R, Stein H, Anagnostopoulos I, Janz M, Cockerill PN, Siebert R, Dorken B, Bonifer C, Mathas S Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma. Nat. Med., 2010-05-02;16(5):571-9. 2010-05-02 [PMID: 20436485] (Control, Human)
• Wuest TR, Carr DJ VEGF-A expression by HSV-1-infected cells drives corneal lymphangiogenesis. J. Exp. Med., 2009-12-21;207(1):101-15, S1-2. 2009-12-21 [PMID: 20026662] (Control, Mouse)
• Yamayoshi S, Yamashita Y, Li J, Hanagata N, Minowa T, Takemura T, Koike S Scavenger receptor B2 is a cellular receptor for enterovirus 71. Nat. Med., 2009-06-21;15(7):798-801. 2009-06-21 [PMID: 19543282] (Bioassay, Human)
• Cueni LN, Detmar M Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions. Exp. Cell Res., 2009-03-04;315(10):1715-23. 2009-03-04 [PMID: 19268462] (Control, Human)
• Sasaki K, Pardee AD, Okada H, Storkus WJ IL-4 inhibits VLA-4 expression on Tc1 cells resulting in poor tumor infiltration and reduced therapy benefit. Eur. J. Immunol., 2008-10-01;38(10):2865-73. 2008-10-01 [PMID: 18958887] (Control, Mouse)
• Kim YS, Park GB, Lee HK, Song H, Choi IH, Lee WJ, Hur DY Cross-linking of B7-H1 on EBV-transformed B cells induces apoptosis through reactive oxygen species production, JNK signaling activation, and fasL expression. J. Immunol., 2008-11-01;181(9):6158-69. 2008-11-01 [PMID: 18941206] (Control, Human)
• Lim YS, McLaughlin T, Sung TC, Santiago A, Lee KF, O'Leary DD p75(NTR) mediates ephrin-A reverse signaling required for axon repulsion and mapping. Neuron, 2008-09-11;59(5):746-58. 2008-09-11 [PMID: 18786358] (Control, Mouse)
• Passante L, Gaspard N, Degraeve M, Frisen J, Kullander K, De Maertelaer V, Vanderhaeghen P Temporal regulation of ephrin/Eph signalling is required for the spatial patterning of the mammalian striatum. Development, 2008-08-28;135(19):3281-90. 2008-08-28 [PMID: 18755772] (Mouse)
• Xing S, He Y, Ling L, Hou Q, Yu J, Zeng J, Pei Z Blockade of EphB2 enhances neurogenesis in the subventricular zone and improves neurological function after cerebral cortical infarction in hypertensive rats. Brain Res., 2008-07-02;1230(0):237-46. 2008-07-02 [PMID: 18639535] (Control, Rat)
• Unni AM, Bondar T, Medzhitov R Intrinsic sensor of oncogenic transformation induces a signal for innate immunosurveillance. Proc. Natl. Acad. Sci. U.S.A., 2008-01-25;105(5):1686-91. 2008-01-25 [PMID: 18223157] (Control, Mouse)
• Nestor MW, Mok LP, Tulapurkar ME, Thompson SM Plasticity of neuron-glial interactions mediated by astrocytic EphARs. J. Neurosci., 2007-11-21;27(47):12817-28. 2007-11-21 [PMID: 18032653] (Control, Mouse)
• Willis DE, van Niekerk EA, Sasaki Y, Mesngon M, Merianda TT, Williams GG, Kendall M, Smith DS, Bassell GJ, Twiss JL Extracellular stimuli specifically regulate localized levels of individual neuronal mRNAs. J. Cell Biol., 2007-09-04;178(6):965-80. 2007-09-04 [PMID: 17785519] (Control, Rat)
• Kin NW, Sanders VM CD86 regulates IgG1 production via a CD19-dependent mechanism. J. Immunol., 2007-08-01;179(3):1516-23. 2007-08-01 [PMID: 17641017] (Control, Mouse)
• Tsao PN, Chan FT, Wei SC, Hsieh WS, Chou HC, Su YN, Chen CY, Hsu WM, Hsieh FJ, Hsu SM Soluble vascular endothelial growth factor receptor-1 protects mice in sepsis. Crit. Care Med., 2007-08-01;35(8):1955-60. 2007-08-01 [PMID: 17568329] (Control, Mouse)
• Dawson DW, Hong JS, Shen RR, French SW, Troke JJ, Wu YZ, Chen SS, Gui D, Regelson M, Marahrens Y, Morse HC, Said J, Plass C, Teitell MA Global DNA methylation profiling reveals silencing of a secreted form of Epha7 in mouse and human germinal center B-cell lymphomas. Oncogene, 2007-01-29;26(29):4243-52. 2007-01-29 [PMID: 17260020] (Control, Human)
• Cursiefen C, Chen L, Saint-Geniez M, Hamrah P, Jin Y, Rashid S, Pytowski B, Persaud K, Wu Y, Streilein JW, Dana R Nonvascular VEGF receptor 3 expression by corneal epithelium maintains avascularity and vision. Proc. Natl. Acad. Sci. U.S.A., 2006-07-18;103(30):11405-10. 2006-07-18 [PMID: 16849433] (Control, Mouse)
• Wang Y, Ying GX, Liu X, Wang WY, Dong JH, Ni ZM, Zhou CF Induction of ephrin-B1 and EphB receptors during denervation-induced plasticity in the adult mouse hippocampus. Eur. J. Neurosci., 2005-05-01;21(9):2336-46. 2005-05-01 [PMID: 15932593] (Control, Mouse)
• Nishio M, Endo T, Tsukada N, Ohata J, Kitada S, Reed JC, Zvaifler NJ, Kipps TJ Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1alpha. Blood, 2005-04-28;106(3):1012-20. 2005-04-28 [PMID: 15860672] (Control, Human)
• Belibasakis GN, Johansson A, Wang Y, Chen C, Kalfas S, Lerner UH The cytolethal distending toxin induces receptor activator of NF-kappaB ligand expression in human gingival fibroblasts and periodontal ligament cells. Infect. Immun., 2005-01-01;73(1):342-51. 2005-01-01 [PMID: 15618171] (Control, Human)
• Jaskoll T, Witcher D, Toreno L, Bringas P, Moon AM, Melnick M FGF8 dose-dependent regulation of embryonic submandibular salivary gland morphogenesis. Dev. Biol., 2004-04-15;268(2):457-69. 2004-04-15 [PMID: 15063181] (Mouse)
• Dobrzanski P, Hunter K, Jones-Bolin S, Chang H, Robinson C, Pritchard S, Zhao H, Ruggeri B Antiangiogenic and antitumor efficacy of EphA2 receptor antagonist. Cancer Res., 2004-02-01;64(3):910-9. 2004-02-01 [PMID: 14871820] (Control, Rat)
• Viti J, Gulacsi A, Lillien L Wnt regulation of progenitor maturation in the cortex depends on Shh or fibroblast growth factor 2. J. Neurosci., 2003-07-02;23(13):5919-27. 2003-07-02 [PMID: 12843296] (Control, Mouse)
• Murai KK, Nguyen LN, Irie F, Yamaguchi Y, Pasquale EB Control of hippocampal dendritic spine morphology through ephrin-A3/EphA4 signaling. Nat. Neurosci., 2003-02-01;6(2):153-60. 2003-02-01 [PMID: 12496762] (Control, Mouse)

Bioinformatics

• Gene Symbol: IGHG1
• Uniprot:
  • P01857.1()