Protein Rev Antibody

Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. (anti-rev)

Product Discontinued

Protein Rev Antibody Summary

• Immunogen: The immunogen for this antibody was a sequence from 1a.a. to 116a.a. from Protein Rev(a 116a.a. long protein)
• Localization: Cell membrane; single-pass type II membrane protein. Processed form: Secreted protein. Also exists as an extracellular soluble form.
• Specificity: Protein Rev
• Clonality: Polyclonal
• Host: Chicken
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:200-1:500
• Application Notes: Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.

Reactivity Notes

This antibody is reactive against HIV.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Chicken products cannot be exported to Canada.

Alternate Names for Protein Rev Antibody

• Anti repression transactivator protein
• Anti repression transactivator
• art/trs
• HIV1 Rev
• HIV1gp6
• Human immunodeficiency virus 1 Rev
• P19
• Protein Rev
• Regulator of expression of viral proteins
• repression transactivator protein

Background

Protein Rev is a phosphoprotein whose state of phosphorylation is mediated by a specific serine kinase activity present in the nucleus. It is phosphorylated at separate regions by protein kinase CK2 and MAPK. Phosphorylation by CK2 could play a role in Rev down-regulation. Rev appears to act post-transcriptionally to relieve negative repression of Gag and Env production.Protein Rev appears to act post-transcriptionally to relieve negative repression of Gag and Env production.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Uniprot:
  • P04618(Virus)