Prostaglandin E2 Parameter Assay Kit

• Reactivity: All-Multi
• Applications: ELISA
• Conjugate: Biotin

Prostaglandin E2 Parameter Assay Kit Summary

• Background: The Parameter PGE₂ Immunoassay is a 3.5 hour forward sequential competitive enzyme immunoassay designed to measure PGE₂ in cell culture supernates, serum, plasma, and urine.
• Specificity: Measures PGE₂ levels in various samples
• Source: N/A
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Prostaglandin E2 Parameter Assay Kit

• Dinoprostone
• PGE2

Background

Prostaglandin E2 (PGE2) is formed in a variety of cells from prostaglandin H2, which is synthesized from arachidonic acid by the enzyme prostaglandin synthetase. PGE2 has a number of biological actions, including vasodilation, both anti- and proinflammatory action, modulation of sleep/wake cycles, and facilitation of human immunodeficiency virus replication. It elevates cAMP levels, stimulates bone resorption and has thermoregulatory effects. It has been shown to be a regulator of sodium excretion and renal hemodynamics.

⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for Prostaglandin E2/PGE2 (KGE004B)(439)

Publications using KGE004B

• Kolliopoulos, V;Polanek, M;Wong Yan Ling, M;Tiffany, A;Spiller, KL;Harley, BAC; Crosstalk between macrophages and mesenchymal stem cells shape patterns of osteogenesis and immunomodulation in mineralized collagen scaffolds Bioactive materials 2025-02-01 [PMID: 40951788] (Human)
• Lautan, O;Chen, SN;Lu, CC;Huang, YH;Chen, HL;Chih, PS;Chen, RJ; Effect-based high-throughput screening of environmental water samples: Focus on liver toxicity pathways and endocrine disruption Journal of hazardous materials 2025-08-05 [PMID: 40773838] (Human)
• Bae, WJ;Lee, SI; Activating Transcription Factor 3 (ATF3) Regulates Cellular Senescence and Osteoclastogenesis via STAT3/ERK and p65/AP-1 Pathways in Human Periodontal Ligament Cells International journal of molecular sciences 2025-05-21 [PMID: 40430099] (Human)
• Yun, J;Kim, JE; Luteolin targets MKK4 to attenuate particulate matter-induced MMP-1 and inflammation in human keratinocytes Scientific reports 2025-05-15 [PMID: 40374763] (Human)
• Kim, JH;Lee, JH;Koo, YJ;Song, JW; N-actylcysteine inhibits diethyl phthalate-induced inflammation via JNK and STAT pathway in RAW264.7 macrophages BMC molecular and cell biology 2025-04-16 [PMID: 40240934] (Mouse)
• Yang, MY;Chen, HY;Ho, CH;Huang, WC; Impact of Probiotic Supplementation and High-Intensity Interval Training on Primary Dysmenorrhea: A Double-Blind, Randomized Controlled Trial Investigating Inflammation and Hormonal Modulation Nutrients 2025-02-09 [PMID: 40004951] (Human)
• Lee, SA;Lee, CH;Lee, SH;Do, E;Kim, DK;Huh, TL;Kim, CS; Inhibitory Effects of Heat-Processed Gynostemma pentaphyllum Extract (Actiponin®) and Its Components on Cartilage Breakdown in Osteoarthritis International journal of molecular sciences 2025-02-18 [PMID: 40004191] (Rat)
• Zhou, S;Wen, H;He, X;Han, X;Li, H; Pulsed electromagnetic field ameliorates the progression of osteoarthritis via the Sirt1/NF-?B pathway Arthritis research & therapy 2025-02-14 [PMID: 39953605] (Human)
• Yoo, HS;Yoon, YS;Shin, JW;Choi, SI;Son, SH;Jang, YH;Yang, YS;Kim, SY;Kim, YR;Chung, KS;Lee, KT;Kim, NJ; In vitro and in vivo anti-inflammatory and antinociceptive activities of a synthetic hydrangenol derivative: 5-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one International immunopharmacology 2025-01-30 [PMID: 39889413] (Mouse)
• Kim, H;Kim, J;Park, S;Kim, J;Gwon, Y;Lee, M;Park, S; Porcine-Derived Chondroitin Sulfate Sodium Alleviates Osteoarthritis in HTB-94 Cells and MIA-Induced SD Rat Models International journal of molecular sciences 2025-01-09 [PMID: 39859238] (Human)
• Ghasemi Moghaddam, H;Gholami, N;Esfahani, A;Ghoreish, Z;Khalaji, A; Serum vitamin D levels and their correlation with pro-inflammatory prostaglandins in Acute myeloid leukemia: a cross-sectional analysis Scientific reports 2024-12-30 [PMID: 39738707] (Human)
• Pruvost, L;Gerlei, M;Paris, C;Velot, É;Kahn, CJ;Bianchi, A;Linder, M; Chondroitin Sulfate Nanovectorized by LC-PUFAs Nanocarriers Extracted from Salmon (Salmo salar) by Green Process with Decreased Inflammatory Marker Expression in Interleukin-1?-Stimulated Primary Human Chondrocytes In Vitro Culture Marine drugs 2024-12-20 [PMID: 39728145] (Human)
• Lee, HK;Kim, HK;Kim, JY;Kim, JS;Park, J;Kim, MS;Lee, TY;Lim, KH;Park, H;Son, DJ;Hong, JT;Han, SB; Ingenol-3-Angelate Enhances the B Cell Inhibitory Potential of Mesenchymal Stem Cells, Leading to Marked Alleviation of Lupus Symptoms in MRL.faslpr Mice International journal of molecular sciences 2024-11-25 [PMID: 39684336] (Human)
• Terlinden, A;Jacquet, S;Manivong, S;Cullier, A;Cassé, F;Legendre, F;Garcia, AA;Roullin, G;Moldovan, F;Sirois, P;Banquy, X;Galéra, P;Audigié, F;Demoor, M;Bertoni, L; Double-blinded, randomized tolerance study of a biologically enhanced Nanogel with endothelin-1 and bradykinin receptor antagonist peptides via intra-articular injection for osteoarthritis treatment in horses BMC veterinary research 2024-12-04 [PMID: 39633332] (Equine)
• Elkhenany, HA;Linardi, RL;Ortved, KF; Differential modulation of inflammatory cytokines by recombinant IL-10 in IL-1? and TNF-? ? stimulated equine chondrocytes and synoviocytes: impact of washing and timing on cytokine responses BMC veterinary research 2024-12-02 [PMID: 39623412] (Equine)
• Wang, K;Zhang, S;Wang, Y;Wu, X;Wen, L;Meng, T;Jin, X;Li, S;Hong, Y;Ke, J;Xu, Y;Yuan, H;Hu, F; Taprenepag restores maternal-fetal interface homeostasis for the treatment of neurodevelopmental disorders Journal of neuroinflammation 2024-11-28 [PMID: 39609821] (Mouse)
• Lynn, T;Kelleher, ME;Georges, HM;McCauley, EM;Logan, RW;Yonkers, KA;Abrahams, VM; Buprenorphine Induces Human Fetal Membrane Sterile Inflammation bioRxiv : the preprint server for biology 2024-11-22 [PMID: 39605446] (Human)
• Gil, TY;Sim, HY;Lee, HY;Ryu, S;Baek, JS;Kim, DG;Sim, J;An, HJ; Hot-Melt Extrusion Drug Delivery System-Formulated Haematococcus pluvialis Extracts Regulate Inflammation and Oxidative Stress in Lipopolysaccharide-Stimulated Macrophages Marine drugs 2024-11-13 [PMID: 39590792] (Mouse)
• Liu, X;Shen, Q;Cheng, L;Dai, K;Wu, Q;Liu, X;Yao, P;Zeng, L; Synergistic Inhibitory Effects of Tetramethylpyrazine and Evodiamine on Endometriosis Development The Journal of steroid biochemistry and molecular biology 2024-10-30 [PMID: 39486648] (Bioassay, Human)
• Jung, JS;Choi, GH;Lee, H;Ko, Y;Ji, S; The Clinical Effect of a Propolis and Mangosteen Extract Complex in Subjects with Gingivitis: A Randomized, Double-Blind, and Placebo-Controlled Clinical Trial Nutrients 2024-09-05 [PMID: 39275315] (Human)
• Takacs, GP;Garcia, JS;Hodges, CA;Kreiger, CJ;Sherman, A;Harrison, JK; CSF1R Ligands Expressed by Murine Gliomas Promote M-MDSCs to Suppress CD8+ T Cells in a NOS-Dependent Manner Cancers 2024-09-01 [PMID: 39272914] (Mouse)
• Kang, W;Xu, Q;Dong, H;Wang, W;Huang, G;Zhang, J; Eriodictyol attenuates osteoarthritis progression through inhibiting inflammation via the PI3K/AKT/NF-?B signaling pathway Scientific reports 2024-08-14 [PMID: 39143134] (Human)
• Yang, C;Yang, H;Kim, H;Chung, N;Shin, J;Min, H;Lee, K;Lee, JR; Injectable Biomimetic Hydrogel Constructs for Cell-Based Menopausal Hormone Therapy with Reduced Breast Cancer Potential Biomaterials research 2024-08-09 [PMID: 39135549] (Rat)
• Lim, JJ;Vining, KH;Mooney, DJ;Blencowe, BJ; Matrix stiffness-dependent regulation of immunomodulatory genes in human MSCs is associated with the lncRNA CYTOR Proceedings of the National Academy of Sciences of the United States of America 2024-08-06 [PMID: 39074278] (Human)
• Liu, J;Yang, D;Sun, X;Yang, S;Zhang, Y;Li, Q;Deng, S;Dai, H;Wu, X; Mass spectrum oriented metabolomics for evaluating the efficacy and discovering the mechanism of Shaofuzhuyu Decoction for endometriosis of cold coagulation and blood stasis Heliyon 2024-07-15 [PMID: 39071582] (Rat)
• Takacs, GP;Garcia, JS;Hodges, CA;Kreiger, CJ;Sherman, A;Harrison, JK; Glioma-derived M-CSF and IL-34 license M-MDSCs to suppress CD8+ T cells in a NOS-dependent manner bioRxiv : the preprint server for biology 2024-06-06 [PMID: 38895268] (Human)
• Luo, L;Wang, H;Xiong, J;Chen, X;Shen, X;Zhang, H; Echinatin attenuates acute lung injury and inflammatory responses via TAK1-MAPK/NF-?B and Keap1-Nrf2-HO-1 signaling pathways in macrophages PloS one 2024-05-16 [PMID: 38753858] (Mouse)
• Zhou, H;Zou, L;Ren, H;Shen, Z;Lin, Y;Cai, H;Zhang, J; Cathelicidin-BF regulates the AMPK/SIRT1/NF-?B pathway to ameliorate murine osteoarthritis: In vitro and in vivo studie International immunopharmacology 2024-05-07 [PMID: 38718660] (Mouse)
• Lokman, MS;Kassab, R;Salem, FAM;Elshopakey, GE;Hussein, A;Aldarmahi, AA;Theyab, A;Alzahrani, KJ;Hassan, KE;Alsharif, KF;Albrakati, A;Tayyeb, JZ;El-Khadragy, MF;Alkhateeb, MA;Al-Ghamdy, AO;Althagafi, HA;Abdel Moneim, A;El-Hennamy, RE; Asiatic acid rescues intestinal tissue by suppressing molecular, biochemical, and histopathological changes associated with the development of ulcerative colitis Bioscience reports 2024-05-05 [PMID: 38699907] (Rat)
• Taibi, M;Elbouzidi, A;Haddou, M;Baraich, A;Loukili, EH;Moubchir, T;Allali, A;Amine Khoulati, ;Bellaouchi, R;Asehraou, A;Addi, M;Salamatullah, AM;Bourhia, M;Siddique, F;El Guerrouj, B;Chaabane, K; Phytochemical characterization and multifaceted bioactivity assessment of essential oil from Ptychotis verticillata Duby: Anti-diabetic, anti-tyrosinase, and anti-inflammatory activity Heliyon 2024-04-30 [PMID: 38699706] (Mouse)
• Lee, YM;Kim, DS; Analgesic, Anti-Inflammatory, and Chondroprotective Activities of Siraitia grosvenorii Residual Extract International journal of molecular sciences 2024-04-12 [PMID: 38673854] (Human)
• Kim, H;Jung, J;Lee, M;Kim, M;Kang, N;Kim, OK;Lee, J; Curcuma longa L. extract exhibits anti-inflammatory and cytoprotective functions in the articular cartilage of monoiodoacetate-injected rats Food & nutrition research 2024-03-19 [PMID: 38571919] (Rat)
• Choi, YJ;Jung, JI;Bae, J;Lee, JK;Kim, EJ; Evaluating the Anti-Osteoarthritis Potential of Standardized Boswellia serrata Gum Resin Extract in Alleviating Knee Joint Pathology and Inflammation in Osteoarthritis-Induced Models International journal of molecular sciences 2024-03-12 [PMID: 38542192] (Rat)
• Sun, J;Song, X;Wang, C;Ruan, Q; Geniposidic acid alleviates osteoarthritis progression through inhibiting inflammation and chondrocytes ferroptosis Journal of cellular and molecular medicine 2024-04-01 [PMID: 38520209] (Mouse)
• Ocampo, YC;Castro, JP;Pájaro, IB;Caro, D;Talero, E;Motilva, V;Franco, LA; Protective effect of sucrose esters from cape gooseberry (Physalis peruviana L.) in TNBS-induced colitis PloS one 2024-03-21 [PMID: 38512973] (Mouse)
• Jantaruk, P;Roytrakul, S;Sistayanarain, A;Kunthalert, D; The pomegranate-derived peptide Pug-4 alleviates nontypeable Haemophilus influenzae-induced inflammation by suppressing NF-kB signaling and NLRP3 inflammasome activation PeerJ 2024-02-20 [PMID: 38406294] (Human, Mouse)
• Stachowicz-Suhs, M;?ab?d?, N;Anisiewicz, A;Banach, J;K?opotowska, D;Milczarek, M;Piotrowska, A;Dzi?giel, P;Maciejczyk, A;Matkowski, R;Wietrzyk, J; Calcitriol promotes M2 polarization of tumor-associated macrophages in 4T1 mouse mammary gland cancer via the induction of proinflammatory cytokines Scientific reports 2024-02-15 [PMID: 38355711] (Mouse)
• Deng, C;Presle, N;Pizard, A;Guillaume, C;Bianchi, A;Kempf, H; Beneficial Impact of Eicosapentaenoic Acid on the Adverse Effects Induced by Palmitate and Hyperglycemia on Healthy Rat Chondrocyte International journal of molecular sciences 2024-02-02 [PMID: 38339087] (Rat)
• Kim, H;Jin, B;Lee, C;Kim, D;Lee, A;Lee, S;An, H; Anti-Inflammatory Effect of Chestnut Honey and Cabbage Mixtures Alleviates Gastric Mucosal Damage Nutrients 2024-01-29 [PMID: 38337674] (Rat)
• Kim, J;Ryu, G;Seo, J;Go, M;Kim, G;Yi, S;Kim, S;Lee, H;Lee, JY;Kim, HS;Park, MC;Shin, DH;Shim, H;Kim, W;Lee, SY; 5-aminosalicylic acid suppresses osteoarthritis through the OSCAR-PPAR? axis Nature communications 2024-02-03 [PMID: 38310093] (Mouse)
• Liu, Z;Lee, H;Dong, L;Cheong, SH;Lee, DS; Fatsia japonica extract exerts antioxidant and anti-neuroinflammatory effects on neuronal cells and a zebrafish model Journal of ethnopharmacology 2024-01-26 [PMID: 38281691] (Mouse)
• Jayawardhana, HHACK;Liyanage, NM;Nagahawatta, DP;Lee, HG;Jeon, YJ;Kang, SI; Pepsin Hydrolysate from Surimi Industry-Related Olive Flounder Head Byproducts Attenuates LPS-Induced Inflammation and Oxidative Stress in RAW 264.7 Macrophages and In Vivo Zebrafish Model Marine drugs 2023-12-28 [PMID: 38248649] (Mouse)
• Chervet, A;Nehme, R;Decombat, C;Longechamp, L;Habanjar, O;Rousset, A;Fraisse, D;Blavignac, C;Filaire, E;Berthon, JY;Delort, L;Caldefie-Chezet, F; Exploring the Therapeutic Potential of Ampelopsis grossedentata Leaf Extract as an Anti-Inflammatory and Antioxidant Agent in Human Immune Cells International journal of molecular sciences 2023-12-28 [PMID: 38203587] (Human)
• Liu, G;Bae, KB;Yang, Y;Lee, BN;Hwang, YC; Icariin negatively regulated lipopolysaccharide-induced inflammation and ameliorated the odontogenic activity of human dental pulp cells in vitro Heliyon 2023-12-01 [PMID: 38144358] (Human)
• Hossain, MA;Lim, S;Bhilare, KD;Alam, MJ;Chen, B;Vijayakumar, A;Yoon, H;Kang, CW;Kim, JH; Bone marrow stem cells incubated with ellipticine regenerate articular cartilage by attenuating inflammation and cartilage degradation in rabbit model Journal of veterinary science 2023-11-01 [PMID: 38031520] (Rabbit)
• Erdenebileg, S;Son, YJ;Kim, M;Oidovsambuu, S;Cha, KH;Kwon, J;Jung, DS;Nho, CW; Saposhnikovia divaricata root and its major components ameliorate inflammation and altered gut microbial diversity and compositions in DSS-induced colitis Integrative medicine research 2023-12-01 [PMID: 38024289] (Mouse)
• Jalilian, E;Abolhasani-Zadeh, F;Afgar, A;Samoudi, A;Zeinalynezhad, H;Langroudi, L; Neutralizing tumor-related inflammation and reprogramming of cancer-associated fibroblasts by Curcumin in breast cancer therapy Scientific reports 2023-11-26 [PMID: 38008819] (Human)
• Bi, W;Bao, K;Zhou, X;Deng, Y;Li, X;Zhang, J;Lan, X;Zhao, J;Lu, D;Xu, Y;Cen, Y;Cao, R;Xu, M;Zhong, W;Zhu, L; PSMC5 regulates microglial polarization and activation in LPS-induced cognitive deficits and motor impairments by interacting with TLR4 Journal of neuroinflammation 2023-11-24 [PMID: 38001534] (Mouse)
• Yan, Z;Wang, Y;Song, Y;Ma, Y;An, Y;Wen, R;Wang, N;Huang, Y;Wu, X; Phenethylferulate as a natural inhibitor of inflammation in LPS-stimulated RAW 264.7 macrophages: focus on NF-?B, Akt and MAPK signaling pathways BMC complementary medicine and therapies 2023-11-07 [PMID: 37936108] (Mouse)
• Park, JH;Kim, JH;Jang, SI;Cho, BO; Anti-inflammatory of disenecionyl cis-khellactone in LPS-stimulated RAW264.7 cells and the its inhibitory activity on soluble epoxide hydrolase Heliyon 2023-10-01 [PMID: 37876448] (Mouse)
• Beerts, C;Broeckx, SY;Depuydt, E;Tack, L;Van Hecke, L;Chiers, K;Van Brantegem, L;Braun, G;Hellmann, K;de Bouvre, N;Van Bruaene, N;De Ryck, T;Duchateau, L;Van Ryssen, B;Peremans, K;Saunders, JH;Verhoeven, G;Pauwelyn, G;Spaas, JH; Low-dose xenogeneic mesenchymal stem cells target canine osteoarthritis through systemic immunomodulation and homing Arthritis research & therapy 2023-10-03 [PMID: 37789403] (Canine)
• Huh, G;Oh, Y;Jeon, Y;Kang, KS;Kim, SN;Jung, SH;Kim, SH;Kim, YJ; Insampaedok-San Extract Exerts an Immune-Enhancing Effect through NF-?B p65 Pathway Activation BioMed research international 2023-09-22 [PMID: 37780486] (Mouse)
• van Wigcheren, GF;Cuenca-Escalona, J;Stelloo, S;Brake, J;Peeters, E;Horrevorts, SK;Frölich, S;Ramos-Tomillero, I;Wesseling-Rozendaal, Y;van Herpen, CML;van de Stolpe, A;Vermeulen, M;de Vries, IJM;Figdor, CG;Flórez-Grau, G; Myeloid-derived suppressor cells and tolerogenic dendritic cells are distinctively induced by PI3K and Wnt signaling pathways The Journal of biological chemistry 2023-09-20 [PMID: 37739035] (Human)
• Wu, Y;Ying, J;Zhu, X;Xu, C;Wu, L; Pachymic acid suppresses the inflammatory response of chondrocytes and alleviates the progression of osteoarthritis via regulating the Sirtuin 6/NF-?B signal axis International immunopharmacology 2023-08-30 [PMID: 37657246] (Mouse)
• Choi, S;Kim, S;Kim, K;Mony, T;Bae, H;Kim, M;Lee, C;Choi, S;Lee, S;Park, S; Fermented Sprouts of Codonopsis lanceolata Suppress LPS-Induced Inflammatory Responses by Inhibiting NF-kappa B Signaling Pathway in RAW 264.7 Macrophages and CD1 Mice Pharmaceutics 2023-01-01 [PMID: 37513980] (Mouse)
• Kim, HR;Lee, SH;Noh, EM;Choi, B;Seo, HY;Jang, H;Kim, SY;Park, MH; Therapeutic Effect of Enzymatically Hydrolyzed Cervi Cornu Collagen NP-2007 and Potential for Application in Osteoarthritis Treatment International journal of molecular sciences 2023-07-19 [PMID: 37511425] (Rat)
• Liyanage, NM;Lee, HG;Nagahawatta, DP;Jayawardhana, HHACK;Song, KM;Choi, YS;Jeon, YJ;Kang, MC; Fucoidan from Sargassum autumnale Inhibits Potential Inflammatory Responses via NF-kappa B and MAPK Pathway Suppression in Lipopolysaccharide-Induced RAW 264.7 Macrophages Marine drugs 2023-06-25 [PMID: 37504905] (Mouse)
• Torre, E;Pinton, G;Lombardi, G;Fallarini, S; Melanoma Cells Inhibit iNKT Cell Functions via PGE2 and IDO1 Cancers 2023-07-05 [PMID: 37444608] (Human)
• Tanabe, N;Tomita, K;Manaka, S;Ichikawa, R;Takayama, T;Kawato, T;Ono, M;Masai, Y;Utsu, A;Suzuki, N;Sato, S; Co-Stimulation of AGEs and LPS Induces Inflammatory Mediators through PLC gamma 1/JNK/NF-kappa B Pathway in MC3T3-E1 Cells Cells 2023-05-13 [PMID: 37408216] (Mouse)
• Rahman, M;Upadhyay, S;Ganguly, K;Introna, M;Ji, J;Boman, C;Muala, A;Blomberg, A;Sandström, T;Palmberg, L; Comparable Response Following Exposure to Biodiesel and Diesel Exhaust Particles in Advanced Multicellular Human Lung Models Toxics 2023-06-14 [PMID: 37368632] (Human)
• Han, SJ;Lee, H;Nam, J;Pan, CH;Jeon, J;Yang, S; Schisandra extract ameliorates arthritis pathogenesis by suppressing the NF-?B and MAPK signalling pathways Journal of cellular and molecular medicine 2023-06-20 [PMID: 37337779] (Mouse)
• Lou, C;Lin, C;Wang, W;Jiang, H;Cai, T;Lin, S;Xue, X;Lin, J;Pan, X; Extracts of Oldenlandia diffusa protects chondrocytes via inhibiting apoptosis and associated inflammatory response in osteoarthritis Journal of ethnopharmacology 2023-06-07 [PMID: 37295574] (Mouse)
• Song, M;Qian, C;Zhang, T;Tang, Y;Zhou, Y;Wei, Z;Wang, A;Zhong, C;Zhao, Y;Lu, Y; Salvia mitiorrhiza Bunge aqueous extract attenuates infiltration of tumor-associated macrophages and potentiates anti-PD-L1 immunotherapy in colorectal cancer through modulating Cox2/PGE2 cascade Journal of ethnopharmacology 2023-06-05 [PMID: 37286115] (Xenograft)
• Wang, C;Kim, IJ;Seong, HR;Noh, CH;Park, S;Kim, TM;Jeong, HS;Kim, KY;Kim, ST;Yuk, HG;Kwon, SC;Choi, EK;Kim, YB; Antioxidative and Anti-Inflammatory Activities of Rosebud Extracts of Newly Crossbred Roses Nutrients 2023-05-19 [PMID: 37242259] (Rat)
• Kim, GO;Park, DH;Bae, JS; Protective Effects of Cirsilineol against Lipopolysaccharide-Induced Inflammation; Insights into HO-1, COX-2, and iNOS Modulation International journal of molecular sciences 2023-05-10 [PMID: 37239882] (Human)
• Zhang, P;Jin, Y;Xia, W;Wang, X;Zhou, Z; Phillygenin inhibits inflammation in chondrocytes via the Nrf2/NF-?B axis and ameliorates osteoarthritis in mice Journal of orthopaedic translation 2023-07-01 [PMID: 37197096] (Mouse)
• Wang, Z;Ma, J;Miao, Z;Sun, Y;Dong, M;Lin, Y;Wu, Y;Sun, Z; Ergothioneine inhibits the progression of osteoarthritis via the Sirt6/NF-?B axis both in vitro and in vivo International immunopharmacology 2023-05-06 [PMID: 37156032] (Rat)
• H Lee, Z Liu, L Dong, DY Lee, D Yoon, H Oh, YC Kim, RB An, DS Lee Anti-Neuroinflammatory and Neuroprotective Effect of Intermedin B Isolated from the Curcuma longa L. via NF-kappaB and ROS Inhibition in BV2 Microglia and HT22 Hippocampal Cells International Journal of Molecular Sciences, 2023-04-17;24(8):. 2023-04-17 [PMID: 37108568] (Mouse)
• KW Samarakoon, AI Kuruppu, JY Ko, JH Lee, YJ Jeon Structural Characterization and Anti-Inflammatory Effects of 24-Methylcholesta-5(6), 22-Diene-3beta-ol from the Cultured Marine Diatom Phaeodactylum tricornutum; Attenuate Inflammatory Signaling Pathways Marine Drugs, 2023-04-03;21(4):. 2023-04-03 [PMID: 37103370] (Mouse)
• SR Park, MG Kook, SR Kim, JW Lee, CH Park, BC Oh, Y Jung, IS Hong Development of cell-laden multimodular Lego-like customizable endometrial tissue assembly for successful tissue regeneration Biomaterials research, 2023-04-21;27(1):33. 2023-04-21 [PMID: 37085887] (Human)
• HR Lee, YJ Jeong, JW Lee, J Jhun, HS Na, KH Cho, SJ Kim, ML Cho, TH Heo Tannic acid, an IL-1beta-direct binding compound, ameliorates IL-1beta-induced inflammation and cartilage degradation by hindering IL-1beta-IL-1R1 interaction PLoS ONE, 2023-04-20;18(4):e0281834. 2023-04-20 [PMID: 37079558] (Human)
• HR Lee, YJ Jeong, JW Lee, J Jhun, HS Na, KH Cho, SJ Kim, ML Cho, TH Heo Tannic acid, an IL-1beta-direct binding compound, ameliorates IL-1beta-induced inflammation and cartilage degradation by hindering IL-1beta-IL-1R1 interaction PLoS ONE, 2023;18(4):e0281834. 2023 [PMID: 37079558] (Human)
• X Wang, D Wang, B Deng, L Yan Syringaresinol attenuates osteoarthritis via regulating the NF-kappaB pathway International immunopharmacology, 2023-03-28;118(0):109982. 2023-03-28 [PMID: 36989902] (Mouse)
• E Kuca-Warna, W Kurowska, M Pleba?czyk, A Wajda, A Kornatka, T Burakowski, I Janicka, P Syrówka, U Skalska Basic Properties of Adipose-Derived Mesenchymal Stem Cells of Rheumatoid Arthritis and Osteoarthritis Patients Pharmaceutics, 2023-03-20;15(3):. 2023-03-20 [PMID: 36986863] (Human)
• EA Ross, LA Turner, H Donnelly, A Saeed, MP Tsimbouri, KV Burgess, G Blackburn, V Jayawarna, Y Xiao, MAG Oliva, J Willis, J Bansal, P Reynolds, JA Wells, J Mountford, M Vassalli, N Gadegaard, ROC Oreffo, M Salmeron-S, MJ Dalby Nanotopography reveals metabolites that maintain the immunomodulatory phenotype of mesenchymal stromal cells Nature Communications, 2023-02-10;14(1):753. 2023-02-10 [PMID: 36765065] (Human)
• J Cholet, C Decombat, L Delort, M Gainche, A Berry, C Ogeron, I Ripoche, M Vareille-D, M Vermerie, D Fraisse, C Felgines, A Rossary, E Ranouille, JY Berthon, A Tourrette, J Priam, E Saunier, Y Troin, F Senejoux, P Chalard, F Caldefie-C Potential Anti-Inflammatory and Chondroprotective Effect of Luzula sylvatica International Journal of Molecular Sciences, 2022-12-21;24(1):. 2022-12-21 [PMID: 36613576] (Human)
• S Lin, J Lu, Q Chen, H Jiang, C Lou, C Lin, W Wang, J Lin, X Pan, X Xue Plantamajoside suppresses the activation of NF-kappaB and MAPK and ameliorates the development of osteoarthritis International immunopharmacology, 2022-12-28;115(0):109582. 2022-12-28 [PMID: 36584575] (Mouse)
• ZH Al-Oanzi, FO Alenazy, HH Alhassan, MR El-Aassar, AI Alzarea, SI Alzarea, AM Abbas, MH Alanazi, MM Al-Enazi Effects of Thymoquinone Alone or in Combination with Losartan on the Cardiotoxicity Caused by Oxidative Stress and Inflammation in Hypercholesterolemia Journal of cardiovascular development and disease, 2022-12-01;9(12):. 2022-12-01 [PMID: 36547425] (Rat)
• R Jeske, X Chen, S Ma, EZ Zeng, T Driscoll, Y Li Bioreactor Expansion Reconfigures Metabolism and Extracellular Vesicle Biogenesis of Human Adipose-derived Stem Cells In Vitro Biochemical engineering journal, 2022-11-02;188(0):. 2022-11-02 [PMID: 36540623] (Human)
• J Wu, H Li, F Hu, P Luo Stevioside attenuates osteoarthritis via regulating Nrf2/HO-1/NF-kappaB pathway Journal of Orthopaedic Translation, 2022-11-15;38(0):190-202. 2022-11-15 [PMID: 36439628] (Mouse)
• EL Ngu, CY Tan, NJ Lai, KH Wong, SH Lim, LC Ming, KO Tan, SM Phang, YY Yow Spirulina platensis Suppressed iNOS and Proinflammatory Cytokines in Lipopolysaccharide-Induced BV2 Microglia Metabolites, 2022-11-20;12(11):. 2022-11-20 [PMID: 36422287] (Mouse)
• B Li, M Wang, S Chen, M Li, J Zeng, S Wu, Y Tu, Y Li, R Zhang, F Huang, X Tong Baicalin Mitigates the Neuroinflammation through the TLR4/MyD88/NF-kappaB and MAPK Pathways in LPS-Stimulated BV-2 Microglia BioMed Research International, 2022-11-09;2022(0):3263446. 2022-11-09 [PMID: 36408278] (Mouse)
• C Jia, F Hu, D Lu, H Jin, H Lu, E Xue, D Wu Formononetin inhibits IL-1beta-induced inflammation in human chondrocytes and slows the progression of osteoarthritis in rat model via the regulation of PTEN/AKT/NF-kappaB pathway International immunopharmacology, 2022-10-25;113(0):109309. 2022-10-25 [PMID: 36306560] (Human, Rat)
• SA El Kazafy, YM Fouad, AF Said, HH Assal, TM Ali, AE Ahmed, BH Elesawy, OM Ahmed Correlations between Cytokine Levels, Liver Function Markers, and Neuropilin-1 Expression in Patients with COVID-19 Vaccines, 2022-09-29;10(10):. 2022-09-29 [PMID: 36298501] (Human)
• Y Wu, M Liu, H Zhou, X He, W Shi, Q Yuan, Y Zuo, B Li, Q Hu, Y Xie COX-2/PGE2/VEGF signaling promotes ERK-mediated BMSCs osteogenic differentiation under hypoxia by the paracrine action of ECs Cytokine, 2022-10-07;161(0):156058. 2022-10-07 [PMID: 36209650] (Rat)
• A Hasan, S Devi Ms, G Sharma, V Narayanan, P Sathiyaraj, S Vinayak, S Sunil Vathasura Kudineer, an Andrographis based polyherbal formulation exhibits immunomodulation and inhibits chikungunya virus (CHIKV) under in-vitro conditions Journal of ethnopharmacology, 2022-09-29;0(0):115762. 2022-09-29 [PMID: 36181982] (Mouse)
• N Kim, C Kim, SH Ryu, GO Kim, JS Bae Anti-Inflammatory Effect of Sparstolonin B through Inhibiting Expression of NF-kappaB and STAT-1 International Journal of Molecular Sciences, 2022-09-06;23(18):. 2022-09-06 [PMID: 36142124] (Human)
• GA Estúa-Acos, B Buentello-, FS Magaña-Gue, JE Flores, O Vivanco-Ro, I Castro-Sal, K Zarco-Ávil, MA García-Mej, Y Garfias Human Amniotic Membrane Mesenchymal Stem Cell-Synthesized PGE2 Exerts an Immunomodulatory Effect on Neutrophil Extracellular Trap in a PAD-4-Dependent Pathway through EP2 and EP4 Cells, 2022-09-10;11(18):. 2022-09-10 [PMID: 36139406] (Human)
• MS Piccinno, T Petrachi, M Pignatti, A Murgia, G Grisendi, O Candini, E Resca, V Bergamini, F Ganzerli, A Portone, I Mastrolia, C Chiavelli, I Castelli, D Bernabei, M Tagliazucc, E Bonetti, F Lolli, G De Santis, M Dominici, E Veronesi Human Adipose Mesenchymal Stromal/Stem Cells Improve Fat Transplantation Performance Cells, 2022-09-07;11(18):. 2022-09-07 [PMID: 36139372] (Xenograft)
• Y Mu, L Wang, L Fu, Q Li Knockdown of LMX1B Suppressed Cell Apoptosis and Inflammatory Response in IL-1beta-Induced Human Osteoarthritis Chondrocytes through NF-kappaB and NLRP3 Signal Pathway Mediators of Inflammation, 2022-09-12;2022(0):1870579. 2022-09-12 [PMID: 36133743] (Human)
• Q Sun, Y Zhang, Y Ding, W Xie, H Li, S Li, Y Li, M Cai Inhibition of PGE2 in Subchondral Bone Attenuates Osteoarthritis Cells, 2022-09-05;11(17):. 2022-09-05 [PMID: 36078169] (Mouse)
• M Wu, C Ye, H Li, X Yang, S Zhu, F Zhou, Y Hao, S Chen, S Jiang A Nested Case-Control Study of the Relationship between Salivary Inflammatory Mediators, Periodontal Parameters, and Preterm Birth in a Chinese Population BioMed Research International, 2022-08-18;2022(0):8629680. 2022-08-18 [PMID: 36033560] (Human)
• J Rodríguez-, JM Torres-Are, N Ávila-Vanz, R Springall, R Bojalil, O Infante, C Lerma, JC Echeverría Association of the Heart Rate Variability Response to Active Standing with the Severity of Calcific Aortic Valve Disease: Novel Insights of a Neurocardiovascular Pathology Journal of Clinical Medicine, 2022-08-16;11(16):. 2022-08-16 [PMID: 36013009] (Human)
• HJ Lee, CH Yoon, HJ Kim, JH Ko, JS Ryu, DH Jo, JH Kim, D Kim, JY Oh Ocular microbiota promotes pathological angiogenesis and inflammation in sterile injury-driven corneal neovascularization Mucosal Immunology, 2022-08-19;0(0):. 2022-08-19 [PMID: 35986099] (Mouse)
• S Li, Y Shi, S Zhang, H Li, Z Ye, J Kong, W Hong, Y Tu, J Ren, Z Meftah, C Xie, X Wang, X Zhang Corynoline Alleviates Osteoarthritis Development via the Nrf2/NF-kappaB Pathway Oxidative Medicine and Cellular Longevity, 2022-07-28;2022(0):2188145. 2022-07-28 [PMID: 35941903] (Mouse)
• EH Lim, SK Mun, JJ Kim, DJ Chang, ST Yee Anti-Inflammatory Effects of Phlebia sp. Extract in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages BioMed Research International, 2022-07-14;2022(0):2717196. 2022-07-14 [PMID: 35872858] (Mouse)
• J Zhang, H Zhang, X Ding, J Hu, Y Li, J Zhang, H Wang, S Qi, A Xie, J Shi, M Xiang, Y Bin, G Wang, L Wang, Z Wang Crosstalk between macrophage-derived PGE2 and tumor UHRF1 drives hepatocellular carcinoma progression Theranostics, 2022-05-01;12(8):3776-3793. 2022-05-01 [PMID: 35664070] (Human)
• Z Barcikowsk, ME Grzybowska, P W??, M Jaskulak, M Kurpas, M Sotomski, M Starzec-Pr, E Rajkowska-, R Hansdorfer, K Zorena Effect of Manual Therapy Compared to Ibuprofen on Primary Dysmenorrhea in Young Women-Concentration Assessment of C-Reactive Protein, Vascular Endothelial Growth Factor, Prostaglandins and Sex Hormones Journal of Clinical Medicine, 2022-05-10;11(10):. 2022-05-10 [PMID: 35628817] (Human)
• T Genovese, M Cordaro, R Siracusa, D Impellizze, S Caudullo, E Raffone, F Macrí, L Interdonat, E Gugliandol, C Interlandi, R Crupi, R D'Amico, R Fusco, S Cuzzocrea, R Di Paola Molecular and Biochemical Mechanism of Cannabidiol in the Management of the Inflammatory and Oxidative Processes Associated with Endometriosis International Journal of Molecular Sciences, 2022-05-12;23(10):. 2022-05-12 [PMID: 35628240] (Rat)
• ME Kotas, CM Moore, JG Gurrola, SD Pletcher, AN Goldberg, R Alvarez, S Yamato, PE Bratcher, CA Shaughness, PL Zeitlin, IH Zhang, Y Li, MT Montgomery, K Lee, EK Cope, RM Locksley, MA Seibold, ED Gordon IL-13-programmed airway tuft cells produce PGE2, which promotes CFTR-dependent mucociliary function JCI Insight, 2022-07-08;7(13):. 2022-07-08 [PMID: 35608904] (Mouse)
• WJ Ho, JNP Smith, YS Park, M Hadiono, K Christo, A Jogasuria, Y Zhang, AV Broncano, L Kasturi, DM Dawson, SL Gerson, SD Markowitz, AB Desai 15-PGDH regulates hematopoietic and gastrointestinal fitness during aging PLoS ONE, 2022-05-19;17(5):e0268787. 2022-05-19 [PMID: 35587945] (Mouse)
• R Boi, K Ebefors, M Henricsson, J Borén, J Nyström Modified lipid metabolism and cytosolic phospholipase A2 activation in mesangial cells under pro-inflammatory conditions Scientific Reports, 2022-05-05;12(1):7322. 2022-05-05 [PMID: 35513427] (Human)
• T Genovese, D Impellizze, R D'Amico, M Cordaro, AF Peritore, R Crupi, E Gugliandol, S Cuzzocrea, R Fusco, R Siracusa, R Di Paola Resveratrol Inhibition of the WNT/beta-Catenin Pathway following Discogenic Low Back Pain International Journal of Molecular Sciences, 2022-04-07;23(8):. 2022-04-07 [PMID: 35456908] (Human)
• M Yang, Z Yang, Y Li, S Su, Z Li, D Lu Mechanism of Traditional Tibetan Medicine Grubthobrildkr Alleviated Gastric Ulcer Induced by Acute Systemic Hypoxia in Rats BioMed Research International, 2022-04-05;2022(0):4803956. 2022-04-05 [PMID: 35425842] (Rat)
• P Arora, W Li, X Huang, W Yu, R Huang, Q Jiang, C Chen Metabolic Reconfiguration Activates Stemness and Immunomodulation of PDLSCs International Journal of Molecular Sciences, 2022-04-06;23(7):. 2022-04-06 [PMID: 35409397] (Human)
• Q Zhao, W Dai, HY Chen, RE Jacobs, BV Zlokovic, BT Lund, A Montagne, A Bonnin Prenatal disruption of blood-brain barrier formation via cyclooxygenase activation leads to lifelong brain inflammation Proceedings of the National Academy of Sciences of the United States of America, 2022-04-04;119(15):e2113310119. 2022-04-04 [PMID: 35377817] (Mouse)
• Y Xin, H Ji, E Cho, KB Roh, J You, D Park, E Jung Immune-enhancing effect of water-soluble beta-glucan derived from enzymatic hydrolysis of yeast glucan Biochemistry and Biophysics Reports, 2022-03-27;30(0):101256. 2022-03-27 [PMID: 35368741] (Mouse)
• X Gao, X Kang, H Lu, E Xue, R Chen, J Pan, J Ma Piceatannol suppresses inflammation and promotes apoptosis in rheumatoid arthritis?fibroblast?like synoviocytes by inhibiting the NF?kappaB and MAPK signaling pathways Molecular Medicine Reports, 2022-03-24;25(5):. 2022-03-24 [PMID: 35322865] (Rat)
• Y Yuan, Q Hu, L Liu, F Xie, L Yang, Y Li, C Zhang, H Chen, J Tang, X Shen Dehydrocostus Lactone Suppresses Dextran Sulfate Sodium-Induced Colitis by Targeting the IKKalpha/beta-NF-kappaB and Keap1-Nrf2 Signalling Pathways Frontiers in Pharmacology, 2022-03-07;13(0):817596. 2022-03-07 [PMID: 35321327] (Mouse)
• JH Cai, YT Sun, S Bao HucMSCs-exosomes containing miR-21 promoted estrogen production in ovarian granulosa cells via LATS1-mediated phosphorylation of LOXL2 and YAP General and comparative endocrinology, 2022-03-07;0(0):114015. 2022-03-07 [PMID: 35271888] (Human)
• J Hernandez-, N Abasolo, H Palacios-J, E Foguet-Rom, D Suñol, M Galofré, A Caimari, L Baselga-Es, JM Del Bas, M Mulero Imbalances in TCA, Short Fatty Acids and One-Carbon Metabolisms as Important Features of Homeostatic Disruption Evidenced by a Multi-Omics Integrative Approach of LPS-Induced Chronic Inflammation in Male Wistar Rats International Journal of Molecular Sciences, 2022-02-25;23(5):. 2022-02-25 [PMID: 35269702] (Rat)
• HC Kuo, KF Lee, SL Chen, SC Chiu, LY Lee, WP Chen, CC Chen, CH Chu Neuron-Microglia Contacts Govern the PGE2 Tolerance through TLR4-Mediated de Novo Protein Synthesis Biomedicines, 2022-02-10;10(2):. 2022-02-10 [PMID: 35203628] (Mouse)
• Z Zhou, L Zhang, Y Liu, C Huang, W Xia, H Zhou, Z Zhou, X Zhou Luteolin Protects Chondrocytes from H2O2-Induced Oxidative Injury and Attenuates Osteoarthritis Progression by Activating AMPK-Nrf2 Signaling Oxidative Medicine and Cellular Longevity, 2022-02-01;2022(0):5635797. 2022-02-01 [PMID: 35154568] (Mouse)
• E Kuca-Warna, M Olesi?ska, P Szcz?sny, E Kontny Impact and Possible Mechanism(s) of Adipose Tissue-Derived Mesenchymal Stem Cells on T-Cell Proliferation in Patients With Rheumatic Disease Frontiers in Physiology, 2022-01-13;12(0):749481. 2022-01-13 [PMID: 35095547] (Human)
• A Gallo, N Cuscino, F Contino, M Bulati, M Pampalone, G Amico, G Zito, C Carcione, C Centi, A Bertani, PG Conaldi, V Miceli Changes in the Transcriptome Profiles of Human Amnion-Derived Mesenchymal Stromal/Stem Cells Induced by Three-Dimensional Culture: A Potential Priming Strategy to Improve Their Properties International Journal of Molecular Sciences, 2022-01-13;23(2):. 2022-01-13 [PMID: 35055049] (Human)
• D Lee, H Jo, C Go, Y Jang, N Chu, S Bae, D Kang, Y Kim, JS Kang The Roles of IL-22 and Its Receptor in the Regulation of Inflammatory Responses in the Brain International Journal of Molecular Sciences, 2022-01-11;23(2):. 2022-01-11 [PMID: 35054942] (Mouse)
• JJ Tang, LF Huang, JL Deng, YM Wang, C Guo, XN Peng, Z Liu, JM Gao Cognitive enhancement and neuroprotective effects of OABL, a sesquiterpene lactone in 5xFAD Alzheimer's disease mice model Redox Biology, 2022-01-08;50(0):102229. 2022-01-08 [PMID: 35026701] (Mouse)
• SW Shin, YS Hwang Anti-Periodontitis Effect of Ethanol Extracts of Alpinia Katsumadai Seeds Nutrients, 2021-12-28;14(1):. 2021-12-28 [PMID: 35011011] (Human)
• KM Kim, SY Kim, TJ Mony, HJ Bae, SD Han, ES Lee, SH Choi, SH Hong, SD Lee, SJ Park Dracocephalum moldavica Ethanol Extract Suppresses LPS-Induced Inflammatory Responses through Inhibition of the JNK/ERK/NF-kappaB Signaling Pathway and IL-6 Production in RAW 264.7 Macrophages and in Endotoxic-Treated Mice Nutrients, 2021-12-16;13(12):. 2021-12-16 [PMID: 34960054] (Mouse)
• A Stemmler, J Symmank, J Steinmetz, K von Brande, CL Hennig, C Jacobs GDF15 Supports the Inflammatory Response of PdL Fibroblasts Stimulated by P. gingivalis LPS and Concurrent Compression International Journal of Molecular Sciences, 2021-12-19;22(24):. 2021-12-19 [PMID: 34948405] (Human)
• X Hu, YA Zhang, B Chen, Z Jin, ML Lin, M Li, HX Mei, JC Lu, YQ Gong, SW Jin, SX Zheng Protectin DX promotes the inflammatory resolution via activating COX-2/L-PGDS-PGD2 and DP1 receptor in acute respiratory distress syndrome International immunopharmacology, 2021-11-10;102(0):108348. 2021-11-10 [PMID: 34920958] (Rat)
• R Shvartsur, G Agam, A Shnaider, S Uzzan, A Nassar, A Jabarin, N Abu-Freha, K Meir, AN Azab Safety and Efficacy of Combined Low-Dose Lithium and Low-Dose Aspirin: A Pharmacological and Behavioral Proof-of-Concept Study in Rats Pharmaceutics, 2021-11-01;13(11):. 2021-11-01 [PMID: 34834241] (Rat)
• RH Mohamed, A Khalphalla, K Nakada, E Elmeligy, D Hassan, EA Ebissy, RA Ghandour, SA Mousa, ASA Hassaneen Clinical and Correlated Responses among Steroid Hormones and Oxidant/Antioxidant Biomarkers in Pregnant, Non-Pregnant and Lactating CIDR-Pre-Synchronized Dromedaries (Camelus dromedarius) Veterinary sciences, 2021-10-21;8(11):. 2021-10-21 [PMID: 34822620] (Camel)
• CH Lee, CF Chiang, FC Kuo, SC Su, CL Huang, JS Liu, CH Lu, CH Hsieh, CC Wang, CH Lee, PH Shen High-Molecular-Weight Hyaluronic Acid Inhibits IL-1beta-Induced Synovial Inflammation and Macrophage Polarization through the GRP78-NF-kappaB Signaling Pathway International Journal of Molecular Sciences, 2021-11-03;22(21):. 2021-11-03 [PMID: 34769349] (Human)
• H Mohammadpo, CR MacDonald, PL McCarthy, SI Abrams, EA Repasky beta2-adrenergic receptor signaling regulates metabolic pathways critical to myeloid-derived suppressor cell function within the TME Cell Reports, 2021-10-26;37(4):109883. 2021-10-26 [PMID: 34706232] (Human, Mouse)
• MR Shin, JH Lee, JA Lee, MJ Kim, HJ Park, BW Park, SB Seo, SS Roh Immunomodulatory and anti-inflammatory effects of Phellinus linteus mycelium BMC complementary medicine and therapies, 2021-10-26;21(1):269. 2021-10-26 [PMID: 34702240] (Human)
• G Jang, S Lee, J Hong, B Park, D Kim, C Kim Anti-Inflammatory Effect of 4,5-Dicaffeoylquinic Acid on RAW264.7 Cells and a Rat Model of Inflammation Nutrients, 2021-10-09;13(10):. 2021-10-09 [PMID: 34684537] (Mouse)
• E Pape, M Parent, A Pinzano, A Sapin-Mine, C Henrionnet, P Gillet, J Scala-Bert, N Gambier Rapamycin-loaded Poly(lactic-co-glycolic) acid nanoparticles: Preparation, characterization, and in vitro toxicity study for potential intra-articular injection International journal of pharmaceutics, 2021-10-16;609(0):121198. 2021-10-16 [PMID: 34662644] (Human)
• Y Wang, H Zhang, M Wang, J He, H Guo, L Li, J Wang CCNB2/SASP/Cathepsin B & PGE2 Axis Induce Cell Senescence Mediated Malignant Transformation International journal of biological sciences, 2021-08-13;17(13):3538-3553. 2021-08-13 [PMID: 34512164] (Human)
• L Dai, Q Wang, X Lv, F Gao, Z Chen, Y Shen Elevated beta-secretase 1 expression mediates CD4+ T cell dysfunction via PGE2 signalling in Alzheimer's disease Brain, Behavior, and Immunity, 2021-09-06;98(0):337-348. 2021-09-06 [PMID: 34500034] (Mouse)
• J Cheng, Z Xie, S Wang, S Wen, S Niu, C Shi, L Yu, X Xu Cough hypersensitivity in patients with metabolic syndrome: a clinical finding and its possible mechanisms BMC pulmonary medicine, 2021-09-06;21(1):284. 2021-09-06 [PMID: 34488706] (Human)
• S Liu, Q Wang, Z Li, L Ma, T Li, Y Li, N Wang, C Liu, P Xue, C Wang TRPV1 Channel Activated by the PGE2/EP4 Pathway Mediates Spinal Hypersensitivity in a Mouse Model of Vertebral Endplate Degeneration Oxidative Medicine and Cellular Longevity, 2021-08-21;2021(0):9965737. 2021-08-21 [PMID: 34471470] (Mouse)
• JJ Shi, HF Liu, T Hu, X Gao, YB Zhang, WR Li, Q Wang, SJ Zhang, D Tang, YB Chen Danggui-Shaoyao-San improves cognitive impairment through inhibiting O-GlcNAc-modification of estrogen alpha receptor in female db/db mice Journal of ethnopharmacology, 2021-08-23;281(0):114562. 2021-08-23 [PMID: 34438027] (Mouse)
• JJ Tang, MR Wang, S Dong, LF Huang, QR He, JM Gao 1,10-Seco-Eudesmane sesquiterpenoids as a new type of anti-neuroinflammatory agents by suppressing TLR4/NF-kappaB/MAPK pathways European Journal of Medicinal Chemistry, 2021-07-21;224(0):113713. 2021-07-21 [PMID: 34315042] (Mouse)
• H Lee, Z Liu, CS Yoon, L Dong, W Ko, ER Woo, DS Lee Anti-Neuroinflammatory and Anti-Inflammatory Activities of Phenylheptatriyne Isolated from the Flowers of Coreopsis lanceolata L. via NF-kappaB Inhibition and HO-1 Expression in BV2 and RAW264.7 Cells International Journal of Molecular Sciences, 2021-07-13;22(14):. 2021-07-13 [PMID: 34299102] (Mouse)
• P Zhu, Z Wang, Z Sun, B Liao, Y Cai Recombinant platelet-derived growth factor-BB alleviates osteoarthritis in a rat model by decreasing chondrocyte apoptosis in vitro and in vivo Journal of Cellular and Molecular Medicine, 2021-07-11;0(0):. 2021-07-11 [PMID: 34250725] (Rat)
• C Park, H Lee, S Hong, IMN Molagoda, JW Jeong, CY Jin, GY Kim, SH Choi, SH Hong, YH Choi Inhibition of Lipopolysaccharide-Induced Inflammatory and Oxidative Responses by Trans-cinnamaldehyde in C2C12 Myoblasts International Journal of Medical Sciences, 2021-04-23;18(12):2480-2492. 2021-04-23 [PMID: 34104079] (Human)
• HJ Kim, YJ Kim, W Park Berberine modulates hyper-inflammation in mouse macrophages stimulated with polyinosinic-polycytidylic acid via calcium-CHOP/STAT pathway Scientific Reports, 2021-05-28;11(1):11298. 2021-05-28 [PMID: 34050236] (Mouse)
• BO Cho, JY Shin, HJ Kang, JH Park, S Hao, F Wang, SI Jang Anti?inflammatory effect of Chrysanthemum zawadskii, peppermint, Glycyrrhiza glabra herbal mixture in�lipopolysaccharide?stimulated RAW264.7 macrophages Molecular Medicine Reports, 2021-05-26;24(1):. 2021-05-26 [PMID: 34036392] (Mouse)
• K Battiston, I Parrag, M Statham, D Louka, H Fischer, G Mackey, A Daley, F Gu, E Baldwin, B Yang, B Muirhead, EA Hicks, H Sheardown, L Kalachev, C Crean, J Edelman, JP Santerre, W Naimark Polymer-free corticosteroid dimer implants for controlled and sustained drug delivery Nature Communications, 2021-05-17;12(1):2875. 2021-05-17 [PMID: 34001908] (Human)
• R Jeske, S Lewis, AC Tsai, K Sanders, C Liu, X Yuan, Y Li Agitation in a Microcarrier-based Spinner Flask Bioreactor Modulates Homeostasis of Human Mesenchymal Stem Cells Biochemical engineering journal, 2021-01-27;168(0):. 2021-01-27 [PMID: 33967591] (Human)
• Y Yan, H Zou, X Lian, L Yang Cyclic mechanical stimulation inhibits rheumatoid arthritis fibroblast-like synoviocytes proliferation via cell cycle arrest Journal of biomechanics, 2021-04-08;121(0):110424. 2021-04-08 [PMID: 33873113] (Human)
• YK Ji, SM Lee, NH Kim, NV Tu, YN Kim, JD Heo, EJ Jeong, JR Rho Stereochemical Determination of Fistularins Isolated from the Marine Sponge Ecionemia acervus and Their Regulatory Effect on Intestinal Inflammation Marine Drugs, 2021-03-22;19(3):. 2021-03-22 [PMID: 33809895] (Human)
• E Park, CG Lee, SJ Han, SH Yun, S Hwang, H Jeon, J Kim, CW Choi, S Yang, SY Jeong Antiosteoarthritic Effect of Morroniside in Chondrocyte Inflammation and Destabilization of Medial Meniscus-Induced Mouse Model International Journal of Molecular Sciences, 2021-03-15;22(6):. 2021-03-15 [PMID: 33804203] (Mouse)
• L Bertoni, S Jacquet-Gu, T Branly, M Desancé, F Legendre, M Melin, P Rivory, DJ Hartmann, A Schmutz, JM Denoix, M Demoor, F Audigié, P Galéra Evaluation of Allogeneic Bone-Marrow-Derived and Umbilical Cord Blood-Derived Mesenchymal Stem Cells to Prevent the Development of Osteoarthritis in An Equine Model International Journal of Molecular Sciences, 2021-03-02;22(5):. 2021-03-02 [PMID: 33801461] (Equine)
• Claudia Cantoni, Martina Serra, Erica Parisi, Bruno Azzarone, Angela Rita Sementa, Luigi Aurelio Nasto et al. Stromal-like Wilms tumor cells induce human Natural Killer cell degranulation and display immunomodulatory properties towards NK cells OncoImmunology 2021-03-24 [PMID: 33758675] (Human)
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• N Jones, J Blagih, F Zani, A Rees, DG Hill, BJ Jenkins, CJ Bull, D Moreira, AIM Bantan, JG Cronin, D Avancini, GW Jones, DK Finlay, KH Vousden, EE Vincent, CA Thornton Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation Nature Communications, 2021-02-22;12(1):1209. 2021-02-22 [PMID: 33619282] (Human)
• P Filannino, R Di Cagno, O Vincentini, D Pinto, A Polo, F Maialetti, A Porrelli, M Gobbetti Nutrients Bioaccessibility and Anti-inflammatory Features of Fermented Bee Pollen: A Comprehensive Investigation Frontiers in Microbiology, 2021-02-02;12(0):622091. 2021-02-02 [PMID: 33603725] (Human)
• R Xing, J Yang, R Wang, Y Wang Extracorporeal shock wave therapy for treating primary dysmenorrhea: A randomized controlled trial Medicine, 2021-02-05;100(5):e23798. 2021-02-05 [PMID: 33592837] (Human)
• YN Kim, YK Ji, NH Kim, N Van Tu, JR Rho, EJ Jeong Isoquinolinequinone Derivatives from a Marine Sponge (Haliclona sp.) Regulate Inflammation in In Vitro System of Intestine Marine Drugs, 2021-02-04;19(2):. 2021-02-04 [PMID: 33557170] (Human)
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