Plasma Cell Antibody (LIV3G11 (7B18)) - Azide and BSA Free

Images

 
Immunohistochemistry-Paraffin: Plasma Cell Antibody (LIV3G11 (7B18)) [Azide Free] [NBP2-33162] - Formalin-paraffin human tonsil stained with Plasma Cell Marker MAb (LIV3G11).

Product Details

Summary
Reactivity Hu, Rt(-)Species Glossary
Applications IHC-P
Clone
LIV3G11 (7B18)
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
1.0 mg/ml

Plasma Cell Antibody (LIV3G11 (7B18)) - Azide and BSA Free Summary

Immunogen
Pancreatic cancer related serum mucin was used as the immunogen for the Plasma Cell antibody.
Localization
Cytoplasmic
Specificity
It recognizes an intra-cytoplasmic antigen, which shows a very high degree of specificity for plasma cells. This antigen is present in normal as well as neoplastic plasma cells. Plasma cells, which are large lymphocytes derived from an antigen-specific B cell, secrete antibodies and are responsible for humoral immunity. Plasma cells differentiate from B cells upon stimulation by CD4+ lymphocytes. The B cell acts as an antigen-presenting cell (APC), consuming an offending pathogen, which is taken up by the B cell by phagocytosis and broken down within proteosomes. Plasma cells contain basophilic cytoplasm; their nucleus contains heterochromatin organized in a characteristic cartwheel arrangement. This MAb superbly recognizes normal and neoplastic plasma cells in routine formalin-fixed, paraffin-embedded tissue sections. It is of potential value in identifying myeloma or plasmacytoma in bone marrow or other tissues. It also helps differentiate lympho-plasmacytoid lymphoma from lymphocytic and follicular lymphoma. Note that this MAb is not suitable for staining frozen tissues.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 0.5-1ug/ml
Application Notes
Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to staining.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
10mM PBS - BSA free
Preservative
No Preservative
Concentration
1.0 mg/ml
Purity
Protein A purified

Alternate Names for Plasma Cell Antibody (LIV3G11 (7B18)) - Azide and BSA Free

  • Plasma

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional Plasma Cell Products

Plasma Cell NBP2-33162

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