PD-1/CTLA-4 (Cadonilimab) Antibody - Azide and BSA Free

Cadonilimab bound to PD-1 protein, and then rebounded to secondary antibodies(Anti-Human-IgG-Fc-HRP) , and read OD450. As shown in fig, Cadonilimab bound to in human PD-1 Protein-His, and the EC50 was 0.09436 nM.

Cadonnilimab bound to PD-1-Jukat cells, and then rebounded to fluorescent secondary antibodies(Anti-Human IgG, Fcgamma) , and test by flow cytometry. As shown in fig, Cadonnilimab bound to PD-1-Jukat cells, and the EC50 was 1.071 nM.

Cadonilimab bound to CTLA4 protein, and then rebounded to secondary antibodies(Anti-Human-IgG-Fc-HRP) , and read OD450. As shown in fig, Cadonilimab bound to in human CTLA4 Protein-His, and the EC50 was 0.06733 nM.

Cadonilimab bound to huCTLA4-CHO cells, and then rebounded to fluorescent secondary antibodies(Anti-Human IgG, Fcgamma PE) , and test by flow cytometry. As shown in fig, Cadonilimab bound to huCTLA4-CHO cells, and the EC50 was 27.870 nM.

• Reactivity: Hu
• Applications: ELISA, Flow, Func
• Clonality: Monoclonal
• Host: Human
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

PD-1/CTLA-4 (Cadonilimab) Antibody - Azide and BSA Free Summary

• Description: This product is shipped at ambient temperature. Upon receipt, store immediately at -20C or lower for 12 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
• Immunogen: PD-1/CTLA-4 (Uniprot: Q15116 & P16410)
• Source: CHO
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Human
• Purity: > 90% by SDS-PAGE and HPLC

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Functional
• Theoretical MW: 198.64 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C in powder form. Store at -80C once reconstituted.
• Buffer: Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: > 90% by SDS-PAGE and HPLC
• Reconstitution Instructions: Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.