PCDHGA11 Overexpression Lysate (Denatured) Summary
protocadherin gamma subfamily A, 11
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
50mM Tris-HCl, 2%SDS, 10% glycerol, 2% 2-mercaptoethanol, pH 6.8.
The exact concentration of the protein of interest cannot be determined for overexpression lysates. Please contact technical support for more information.
This transient overexpression cell lysate is useful for western blot and was tested with Anti-PCDHGA11 antibody H00056105-B01 by Western Blots.
Lysate Details for PCDHGA11
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for PCDHGA11 Overexpression Lysate (Denatured)
- protocadherin gamma subfamily A, 11
- protocadherin gamma-A11
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed
for 6 months from date of receipt.
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