Parainfluenza Virus type 1 Antibody (251/12A (PAR1)) - BSA Free

• Reactivity: V-Vi
• Applications: WB, ELISA
• Clone: 251/12A (PAR1)
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free

Parainfluenza Virus type 1 Antibody (251/12A (PAR1)) - BSA Free Summary

• Description: Novus Biologicals Mouse Parainfluenza Virus type 1 Antibody (251/12A (PAR1)) - BSA Free (NB100-63036) is a monoclonal antibody validated for use in WB and ELISA. Anti-Parainfluenza Virus type 1 Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Parainfluenza 1 fusion protein
• Specificity: NB100-63036 specifically recognizes an epitope within the fusion protein of parainfluenza virus 1 (HPIV-1), an enveloped single-stranded RNA virus of the Paramyxoviridae family. Parainfluenza viruses are genetically and antigenically divided into the four types HPIV1-4, with HPIV-1, -2 and -3 being major causative agents of lower respiratory infections in the young and immunologically vulnerable. The fusion protein of all HPIV, is a 60-66kDa surface glycoprotein, integral in the fusion of virus host-cell membranes, and the subsequent infection of a host cell by the viral nucleocapsid.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot
• Application Notes: Use in WB reported in scientific literature (PMID:34529742).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: <0.1% Sodium Azide
• Purity: Protein A purified

Alternate Names for Parainfluenza Virus type 1 Antibody (251/12A (PAR1)) - BSA Free

• HPIV 1
• hPIV1
• Human parainfluenza 1 virus
• Human parainfluenza virus type
• Parainfluenza Type 1
• Parainfluenza

Background

Human parainfluenza viruses (HPIV) were first discovered in the late 1950s. HPIV is genetically and antigenically divided into types 1 to 4. HPIV 1 to HPIV 3 are major causes of lower respiratory infections in infants, young children, the immunocompromised, the chronically ill, and the elderly. Each subtype can cause somewhat unique clinical diseases in different hosts. HPIV are enveloped and of medium size (150 to 250 nm), and their RNA genome is in the negative sense. These viruses belong to the Paramyxoviridae family, one of the largest and most rapidly growing groups of viruses causing significant human and veterinary disease. HPIV are closely related to recently discovered megamyxoviruses (Hendra and Nipah viruses) and metapneumovirus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Parainfluenza Virus type 1 Antibody (NB100-63036)(2)

Publications using NB100-63036

• Wu CT, Lidsky PV, Xiao Y et al. SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogramming Cell 2022-12-01 [PMID: 36580912]
• Kurebayashi Y, Bajimaya S, Watanabe M et al. Human parainfluenza virus type 1 regulates cholesterol biosynthesis and establishes quiescent infection in human airway cells PLOS Pathogens 2021-09-16 [PMID: 34529742] (WB)