Oval Cell Marker Antibody (OC2-3C7) [DyLight 405]


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Product Details

Reactivity MuSpecies Glossary
Applications Flow, ICC/IF, IHC, IHC-Fr
DyLight 405

Oval Cell Marker Antibody (OC2-3C7) [DyLight 405] Summary

This product is provided as conjugated tissue culture supernatant. Due to the crude preparation of the antibody material, excess dye may remain in the final product. We highly recommend taking necessary precautions, such as adding additional wash steps and running proper controls.
Nonparenchymal cells from DDC-treated mice to induce the oval cell response.
Cell surface
Hepatic periductal cell Marker
Specific for both proliferating and normal hepatic periductal cells.
Tissue culture supernatant
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  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
Application Notes
This Oval Cell Marker (OC2-3C7) antibody is useful for Immunohistochemistry on acetone fixed frozen sections and Flow cytometry. Immunocytochemistry/Immunofluorescence was reported in scientific literature.

Reactivity Notes


Packaging, Storage & Formulations

Store at 4C in the dark.
50mM Sodium Borate
0.05% Sodium Azide
Tissue culture supernatant


Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.


Liver is well known to possess facultative stem cells which can be activated in response to injury and hepatic stem cell activation was first described in rat model, wherein, chemical damage in combination with partial hepatectomy resulted in the emergence of a new cell type which was described according to its nuclear morphology as "oval cells". The word 'oval cells' is now employed to define population of small proliferating cells with oval-shaped nuclei which arise within liver tissue following certain types of hepatic injury. Oval cell proliferation is activated when the proliferative capacity of hepatocytes is impaired, as well as in certain models of carcinogenesis. Histologically, hepatic tissue is highly complex and contains many different cell types including various kinds of hepatocytes, ducts, hematopoietic cells, endothelial cells, macrophages, stellate cells etc., and the oval cells have been proposed to be bipotential progenitor cells capable of generating both hepatocytes and bile ducts. Due to their bipotency and high clonogenicity, oval cells have been considered putative liver stem cells and research is in progress for elucidation of signaling molecules involved in controlling the activation, proliferation and differentiation of this unique cell population. Our oval cell antibodies have been developed against hepatic nonparenchymal cells (NPCs) from mice undergoing oval cell activation and with these antibodies, it is now possible to perform microarray analysis of distinct liver cell populations during induced oval cell response or certain pathological conditions.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for Oval Cell Marker Antibody (NBP1-18970V) (0)

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Secondary Antibodies


Isotype Controls

Other Available Formats

Allophycocyanin Labeled NBP1-18970APC
Biotin Labeled NBP1-18970B
DyLight 350 Labeled NBP1-18970UV
DyLight 488 Labeled NBP1-18970G
DyLight 550 Labeled NBP1-18970R
DyLight 650 Labeled NBP1-18970C
DyLight 680 Labeled NBP1-18970FR
DyLight 755 Labeled NBP1-18970IR
FITC Labeled NBP1-18970F
HRP Labeled NBP1-18970H
PE Labeled NBP1-18970PE
PerCP Labeled NBP1-18970PCP

Additional Array Products

Array NBP1-18970V

Research Areas for Oval Cell Marker Antibody (NBP1-18970V)

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