ORF3a Antibody (2819D) [Alexa Fluor® 750]

• Reactivity: V
• Applications: WB, IHC, ICC/IF
• Clone: 2819D
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Alexa Fluor 750

ORF3a Antibody (2819D) [Alexa Fluor® 750] Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: SARS-CoV-2 ORF3a peptide
• Specificity: Detects SARS-CoV-2 ORF3a in Western blots.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ORF3a Antibody (2819D) [Alexa Fluor® 750]

• ORF3a
• U274
• X1

Background

ORF3a is an open reading frame coronavirus protein involved in virus replication in release.  Analysis of ORF3a nucleotide and protein sequences can predict their ability to alter viral cycle and provides insight into the biology of coronaviruses.  ORF3a has been characterized in both SARS-CoV which caused the SARS outbreak and in SARS-CoV-2 which caused the COVID-19 pandemic.  ORF3a is a high priority target that is amenable to drug treatment for COVID-19 post viral syndrome.  Mutations in ORF3a can help understand viral virulence and design suitable therapeutics.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.